NMR spectroscopic in vitro assay using hyperpolarization

Peter Knox (Inventor), Neil Cook (Inventor), Klaes Golman (Inventor), Haukur Johanneson (Inventor), Oksar Axelsson (Inventor), Jan Henrik Ardenkjær-Larsen (Inventor)

Research output: Patent

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An in vitro assay method which comprises the use of an assay reagent containing at least one NMR active nucleus, and hyperpolarising at least one NMR active nucleus of the assay reagent; and analysing the assay reagent and/or the assay by NMR spectroscopy and/or NMR imaging. The assay reagent may contain an artificially high concentration of an NMR active nucleus.

Original languageEnglish
IPCG01R 33/ 465 A I
Patent numberWO0040988
Filing date13/07/2000
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date02/08/1999
Priority numberGB19990018096
Publication statusPublished - 13 Jul 2000
Externally publishedYes

Bibliographical note

Also published as: US7501236 (B1) JP2002534687 (A) IL143927 (A) EP1141738 (A1) CA2356442 (A1) CA2356442 (C) AU1880300 (A) AU766923 (B2)


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