NMR spectroscopic in vitro assay using hyperpolarization

Peter Knox (Inventor), Neil Cook (Inventor), Klaes Golman (Inventor), Haukur Johanneson (Inventor), Oksar Axelsson (Inventor), Jan Henrik Ardenkjær-Larsen (Inventor)

Research output: Patent

18 Downloads (Pure)

Abstract

An in vitro assay method which comprises the use of an assay reagent containing at least one NMR active nucleus, and hyperpolarising at least one NMR active nucleus of the assay reagent; and analysing the assay reagent and/or the assay by NMR spectroscopy and/or NMR imaging. The assay reagent may contain an artificially high concentration of an NMR active nucleus.

Original languageEnglish
IPCG01R 33/ 465 A I
Patent numberWO0040988
Filing date13/07/2000
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date02/08/1999
Priority numberGB19990018096
Publication statusPublished - 13 Jul 2000
Externally publishedYes

Bibliographical note

Also published as: US7501236 (B1) JP2002534687 (A) IL143927 (A) EP1141738 (A1) CA2356442 (A1) CA2356442 (C) AU1880300 (A) AU766923 (B2)

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