Nisin-permeabilized microbial cell catalysts

Christian Solem (Inventor), Qi Wang (Inventor), Peter Ruhdal Jensen (Inventor), Ge Zhao (Inventor), Jianming Liu (Inventor), Robin Dorau (Inventor)

Research output: Patent

24 Downloads (Pure)


A method and use of nisin-permeabilized microbial cells as whole-cell catalysts for reducing the amount of a target substrate in a sample to one of more product are provided. Specifically, a method of reducing the amount of lactose in a dairy sample using nisin-permeabilized lactic acid bacterial cell catalysts, which have been permeabilized by incubating with a nisin producing microbial cell and/or culture medium derived therof. Further provided is a nisin producing microbial cell, derived from parent strain Lactococcus lactis subsp. lactis bv. diacetylactis SD96 (NCBI accession No. SRX6686433).

Original languageEnglish
IPCC12P 19/ 14 A I
Patent numberWO2021160832
Filing date13/02/2020
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date13/02/2020
Priority numberEP20200157131
Publication statusPublished - 19 Aug 2021


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