Nickel Excretion in Urine after Oral Administration

T. Menne, H. I. Mikkelsen, Per Bent Solgaard

    Research output: Contribution to journalJournal articleResearchpeer-review


    In recent years the importance of internal exposure to nickel in patients with recurrent hand eczema and nickel allergy has become evident. The present study was performed in order to investigate the value of urinary nickel determinations as an index of oral nickel intake. After oral administration of 5.6 mg nickel (as the sulfate), increased nickel excretion was found over the following 2-3 days. We conclude that consecutive urinary nickel determinations are able to disclose variations in oral intake of nickel.
    Original languageEnglish
    JournalContact Dermatitis
    Issue number2
    Pages (from-to)106-108
    Publication statusPublished - 1978


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