Newcastle disease outbreaks in recent years in Western Europe were caused by an old (VI) and a novel genotype (VII)

B. Lomniczi, E. Wehmann, J. Herczeg, A. Ballagi-Pordany, E.F. Kaleta, O. Werner, G. Meulemans, Poul Henrik Jørgensen, A.P. Mante, A.L.J. Gielkens, I. Capua, J. Damoser

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    Abstract

    Newcastle disease virus (NDV) strains, isolated from outbreaks during epizootics between 1992 and 1996 in Western European countries, were compared by restriction enzyme cleavage site mapping of the fusion (F) protein gene between nucleotides 334 and 1682 and by sequence analysis between nucleotides 47 and 435. Both methods revealed that NDV strains responsible for these epizootics belong to two distinct genotypes. Strains derived from sporadic cases in Denmark, Sweden, Switzerland and Austria were classified into genotype VI [6], the same group which caused outbreaks in the Middle East and Greece in the late 1960's and in Hungary in the early 1980's. In contrast, viruses that caused epizootics in Germany, Belgium, The Netherlands, Spain and Italy could be classified into a novel genotype (provisionally termed VII), hitherto undetected in Europe. It is possible that the genotype VII viruses originated in the Far East because they showed a high genetic similarity (97%) to NDV strains isolated from Indonesia in the late 1980's.
    Original languageEnglish
    JournalArchives of Virology
    Volume143
    Issue number1
    Pages (from-to)49-64
    ISSN0304-8608
    DOIs
    Publication statusPublished - 1998

    Cite this

    Lomniczi, B., Wehmann, E., Herczeg, J., Ballagi-Pordany, A., Kaleta, E. F., Werner, O., Meulemans, G., Jørgensen, P. H., Mante, A. P., Gielkens, A. L. J., Capua, I., & Damoser, J. (1998). Newcastle disease outbreaks in recent years in Western Europe were caused by an old (VI) and a novel genotype (VII). Archives of Virology, 143(1), 49-64. https://doi.org/10.1007/s007050050267