Neurotrophic factor protein conjugates and related embodiments

Bjøm Voldborg; Stefan Kol; Johnny Arnsdorf; Shaji Joseph; Elizabeth Brunk

Neurotrophic factor protein conjugates and related embodiments

Bjøm Voldborg (Inventor), Stefan Kol (Inventor), Johnny Arnsdorf (Inventor), Shaji Joseph (Inventor), Elizabeth Brunk (Inventor)

Novo Nordisk Foundation Center for Biosustainability

Research output: Patent

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Abstract

Compositions that comprise protein conjugates comprising an NTF and a nontoxic fragment of a Clostridial neurotoxin. Vectors, host cells, and methods of use and making are also described. Pharmaceutical compositions comprising the protein conjugates described herein are used to provide neuroprotection and treat neurodegenerative diseases and neuron damage amongst other things.

Original language	English
IPC	C07K 19/ 00 A I
Patent number	WO2020206375
Filing date	03/04/2020
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	03/04/2019
Priority number	US201962828870P
Publication status	Published - 8 Oct 2020

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title = "Neurotrophic factor protein conjugates and related embodiments",

abstract = "Compositions that comprise protein conjugates comprising an NTF and a nontoxic fragment of a Clostridial neurotoxin. Vectors, host cells, and methods of use and making are also described. Pharmaceutical compositions comprising the protein conjugates described herein are used to provide neuroprotection and treat neurodegenerative diseases and neuron damage amongst other things.",

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AU - Voldborg, Bjøm

AU - Kol, Stefan

AU - Arnsdorf, Johnny

AU - Joseph, Shaji

AU - Brunk, Elizabeth

PY - 2020/10/8

Y1 - 2020/10/8

N2 - Compositions that comprise protein conjugates comprising an NTF and a nontoxic fragment of a Clostridial neurotoxin. Vectors, host cells, and methods of use and making are also described. Pharmaceutical compositions comprising the protein conjugates described herein are used to provide neuroprotection and treat neurodegenerative diseases and neuron damage amongst other things.

AB - Compositions that comprise protein conjugates comprising an NTF and a nontoxic fragment of a Clostridial neurotoxin. Vectors, host cells, and methods of use and making are also described. Pharmaceutical compositions comprising the protein conjugates described herein are used to provide neuroprotection and treat neurodegenerative diseases and neuron damage amongst other things.

M3 - Patent

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Y2 - 2020/04/03

ER -

Neurotrophic factor protein conjugates and related embodiments

Abstract

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