Neurotrophic factor protein conjugates and related embodiments

Bjøm Voldborg (Inventor), Stefan Kol (Inventor), Johnny Arnsdorf (Inventor), Shaji Joseph (Inventor), Elizabeth Brunk (Inventor)

Research output: Patent

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Abstract

Compositions that comprise protein conjugates comprising an NTF and a nontoxic fragment of a Clostridial neurotoxin. Vectors, host cells, and methods of use and making are also described. Pharmaceutical compositions comprising the protein conjugates described herein are used to provide neuroprotection and treat neurodegenerative diseases and neuron damage amongst other things.

Original languageEnglish
IPCC07K 19/ 00 A I
Patent numberWO2020206375
Filing date03/04/2020
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date03/04/2019
Priority numberUS201962828870P
Publication statusPublished - 8 Oct 2020

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