Compositions that comprise protein conjugates comprising an NTF and a nontoxic fragment of a Clostridial neurotoxin. Vectors, host cells, and methods of use and making are also described. Pharmaceutical compositions comprising the protein conjugates described herein are used to provide neuroprotection and treat neurodegenerative diseases and neuron damage amongst other things.
|C07K 19/ 00 A I
|International Bureau of the World Intellectual Property Organization (WIPO)
|Published - 8 Oct 2020