Nature of bacterial colonization influences transcription of mucin genes in mice during the first week of life

Anders Bergström; Matilde Bylov Kristensen; Martin Iain Bahl; Stine B. Metzdorff; Lisbeth Nielsen Fink; Hanne Frøkiær; Tine Rask Licht

doi:10.1186/1756-0500-5-402

Nature of bacterial colonization influences transcription of mucin genes in mice during the first week of life

Anders Bergström
, Matilde Bylov Kristensen
, Martin Iain Bahl
, Stine B. Metzdorff
, Lisbeth Nielsen Fink
, Hanne Frøkiær
, Tine Rask Licht

National Food Institute

University of Copenhagen

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

In summary, our data show that development of the expression of genes encoding secreted (Muc2/Tff3) and membrane-bound (Muc1/Muc3/Muc4) mucus regulatory proteins, respectively, is distinct and that the onset of this development may be accelerated by specific groups of bacteria present or absent at the mucosal site.

Original language	English
Article number	402
Journal	BMC Research Notes
Volume	5
ISSN	1756-0500
DOIs	https://doi.org/10.1186/1756-0500-5-402
Publication status	Published - 2012

Bibliographical note

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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title = "Nature of bacterial colonization influences transcription of mucin genes in mice during the first week of life",

abstract = "In summary, our data show that development of the expression of genes encoding secreted (Muc2/Tff3) and membrane-bound (Muc1/Muc3/Muc4) mucus regulatory proteins, respectively, is distinct and that the onset of this development may be accelerated by specific groups of bacteria present or absent at the mucosal site.",

author = "Anders Bergstr{\"o}m and Kristensen, \{Matilde Bylov\} and Bahl, \{Martin Iain\} and Metzdorff, \{Stine B.\} and Fink, \{Lisbeth Nielsen\} and Hanne Fr{\o}ki{\ae}r and Licht, \{Tine Rask\}",

note = "This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ",

year = "2012",

doi = "10.1186/1756-0500-5-402",

language = "English",

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T1 - Nature of bacterial colonization influences transcription of mucin genes in mice during the first week of life

AU - Bergström, Anders

AU - Kristensen, Matilde Bylov

AU - Bahl, Martin Iain

AU - Metzdorff, Stine B.

AU - Fink, Lisbeth Nielsen

AU - Frøkiær, Hanne

AU - Licht, Tine Rask

N1 - This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PY - 2012

Y1 - 2012

N2 - In summary, our data show that development of the expression of genes encoding secreted (Muc2/Tff3) and membrane-bound (Muc1/Muc3/Muc4) mucus regulatory proteins, respectively, is distinct and that the onset of this development may be accelerated by specific groups of bacteria present or absent at the mucosal site.

AB - In summary, our data show that development of the expression of genes encoding secreted (Muc2/Tff3) and membrane-bound (Muc1/Muc3/Muc4) mucus regulatory proteins, respectively, is distinct and that the onset of this development may be accelerated by specific groups of bacteria present or absent at the mucosal site.

U2 - 10.1186/1756-0500-5-402

DO - 10.1186/1756-0500-5-402

M3 - Journal article

SN - 1756-0500

VL - 5

JO - BMC Research Notes

JF - BMC Research Notes

M1 - 402

ER -

Nature of bacterial colonization influences transcription of mucin genes in mice during the first week of life

Abstract

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