Nanoscale Imaging and Stabilization of Silica Nanospheres in Liquid Phase Transmission Electron Microscopy

Mark J. Meijerink, Cristiano Spiga, Thomas W. Hansen, Christian D. Damsgaard, Krijn P. de Jong, Jovana Zečević*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Abstract

Liquid phase transmission electron microscopy (LP-TEM) is a novel and highly promising technique for the in situ study of important nanoscale processes, in particular the synthesis and modification of various nanostructures in a liquid. Destabilization of the samples, including reduction, oxidation, or dissolution by interactions between electron beam, liquid, and sample, is still one of the main challenges of this technique. This work focuses on amorphous silica nanospheres and the phenomena behind their reshaping and dissolution in LP-TEM. It is proposed that silica degradation is primarily the result of reducing radical formation in the liquid phase and the subsequent accelerated hydroxylation of the silica, while alterations in silica solid structure, pH, and oxidizing species formation had limited influence. Furthermore, the presence of water vapor instead of liquid water also results in degradation of silica. Most importantly however, it is shown that the addition of scavengers for reducing radicals significantly improved amorphous silica stability during LP-TEM imaging. Devising such methods to overcome adverse effects in LP-TEM is of the utmost importance for further development and implementation of this technique in studies of nanoscale processes in liquid.
Original languageEnglish
Article number1800374
JournalParticle & Particle Systems Characterization
Volume36
Issue number1
Number of pages8
ISSN0934-0866
DOIs
Publication statusPublished - 2019

Keywords

  • Electronic beam damage
  • Environmental TEM
  • Liquid phase STEM
  • Radical scavenging
  • Silica nanoparticles

Cite this

@article{67d955accb2349278915e179c4bba286,
title = "Nanoscale Imaging and Stabilization of Silica Nanospheres in Liquid Phase Transmission Electron Microscopy",
abstract = "Liquid phase transmission electron microscopy (LP-TEM) is a novel and highly promising technique for the in situ study of important nanoscale processes, in particular the synthesis and modification of various nanostructures in a liquid. Destabilization of the samples, including reduction, oxidation, or dissolution by interactions between electron beam, liquid, and sample, is still one of the main challenges of this technique. This work focuses on amorphous silica nanospheres and the phenomena behind their reshaping and dissolution in LP-TEM. It is proposed that silica degradation is primarily the result of reducing radical formation in the liquid phase and the subsequent accelerated hydroxylation of the silica, while alterations in silica solid structure, pH, and oxidizing species formation had limited influence. Furthermore, the presence of water vapor instead of liquid water also results in degradation of silica. Most importantly however, it is shown that the addition of scavengers for reducing radicals significantly improved amorphous silica stability during LP-TEM imaging. Devising such methods to overcome adverse effects in LP-TEM is of the utmost importance for further development and implementation of this technique in studies of nanoscale processes in liquid.",
keywords = "Electronic beam damage, Environmental TEM, Liquid phase STEM, Radical scavenging, Silica nanoparticles",
author = "Meijerink, {Mark J.} and Cristiano Spiga and Hansen, {Thomas W.} and Damsgaard, {Christian D.} and {de Jong}, {Krijn P.} and Jovana Zečević",
year = "2019",
doi = "10.1002/ppsc.201800374",
language = "English",
volume = "36",
journal = "Particle & Particle Systems Characterization",
issn = "0934-0866",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "1",

}

Nanoscale Imaging and Stabilization of Silica Nanospheres in Liquid Phase Transmission Electron Microscopy. / Meijerink, Mark J.; Spiga, Cristiano; Hansen, Thomas W.; Damsgaard, Christian D.; de Jong, Krijn P.; Zečević, Jovana.

In: Particle & Particle Systems Characterization, Vol. 36, No. 1, 1800374, 2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Nanoscale Imaging and Stabilization of Silica Nanospheres in Liquid Phase Transmission Electron Microscopy

AU - Meijerink, Mark J.

AU - Spiga, Cristiano

AU - Hansen, Thomas W.

AU - Damsgaard, Christian D.

AU - de Jong, Krijn P.

AU - Zečević, Jovana

PY - 2019

Y1 - 2019

N2 - Liquid phase transmission electron microscopy (LP-TEM) is a novel and highly promising technique for the in situ study of important nanoscale processes, in particular the synthesis and modification of various nanostructures in a liquid. Destabilization of the samples, including reduction, oxidation, or dissolution by interactions between electron beam, liquid, and sample, is still one of the main challenges of this technique. This work focuses on amorphous silica nanospheres and the phenomena behind their reshaping and dissolution in LP-TEM. It is proposed that silica degradation is primarily the result of reducing radical formation in the liquid phase and the subsequent accelerated hydroxylation of the silica, while alterations in silica solid structure, pH, and oxidizing species formation had limited influence. Furthermore, the presence of water vapor instead of liquid water also results in degradation of silica. Most importantly however, it is shown that the addition of scavengers for reducing radicals significantly improved amorphous silica stability during LP-TEM imaging. Devising such methods to overcome adverse effects in LP-TEM is of the utmost importance for further development and implementation of this technique in studies of nanoscale processes in liquid.

AB - Liquid phase transmission electron microscopy (LP-TEM) is a novel and highly promising technique for the in situ study of important nanoscale processes, in particular the synthesis and modification of various nanostructures in a liquid. Destabilization of the samples, including reduction, oxidation, or dissolution by interactions between electron beam, liquid, and sample, is still one of the main challenges of this technique. This work focuses on amorphous silica nanospheres and the phenomena behind their reshaping and dissolution in LP-TEM. It is proposed that silica degradation is primarily the result of reducing radical formation in the liquid phase and the subsequent accelerated hydroxylation of the silica, while alterations in silica solid structure, pH, and oxidizing species formation had limited influence. Furthermore, the presence of water vapor instead of liquid water also results in degradation of silica. Most importantly however, it is shown that the addition of scavengers for reducing radicals significantly improved amorphous silica stability during LP-TEM imaging. Devising such methods to overcome adverse effects in LP-TEM is of the utmost importance for further development and implementation of this technique in studies of nanoscale processes in liquid.

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KW - Environmental TEM

KW - Liquid phase STEM

KW - Radical scavenging

KW - Silica nanoparticles

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JO - Particle & Particle Systems Characterization

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