Nanorods with Biocatalytically Induced SelfElectrophoresis

Ileana-Alexandra Pavel, Ada-Ioana Bunea, Sorin David, Szilveszter Gaspar

Research output: Contribution to journalJournal articleResearchpeer-review


Nanorods with motion enhanced through biocatalytically induced self-electrophoresis are described. To obtain such nanorods, the polymer half of polypyrrole-gold (PPy-Au) nanorods is decorated with horseradish peroxidase (HRP) and their metal half with cytochromec (Cytc). If such nanorods are suspended in enzymatically generated mixtures of O2(-) and H2O2, the immobilized Cytc is reduced by O2(-), and the immobilized HRP is oxidized by H2O2. As both hemeproteins are capable of direct electron transfer to/from solid substrates, the oxidized HRP is subsequently reduced with electrons received, through the nanorod, from the reduced Cytc. The combined processes cause species from the electrical double layer of the nanorods to move from one end of the nanorod to the other, which powers the motion of the nanorods in the opposite direction. The diffusive motion of the hemeprotein-modified nanorods is characterized by a diffusion coefficient 30% larger in the presence of O2(-) and H2O2 than in their absence. Unmodified nanorods do not show such behavior.
Original languageEnglish
Issue number3
Pages (from-to)866-872
Number of pages7
Publication statusPublished - 2014
Externally publishedYes


Dive into the research topics of 'Nanorods with Biocatalytically Induced SelfElectrophoresis'. Together they form a unique fingerprint.

Cite this