Abstract
The proliferation of engineered nanomaterials (ENMs), e.g. in nanomedicine, demands for novel sensitive techniques allowing for the analysis of minute samples. We present nanoelectromechanical system-based IR spectroscopy (NEMS-IR) of picograms of polymeric micelles. The micelles are nebulized with electrospray directly from dispersion and then efficiently collected on the sensor, which detects the IR-wavelength-dependent photothermal sample heating. Only 10 nL of sample (~0.1 mg/mL) is required for the acquisition of an IR spectrum. Measurement, including sample preparation, takes only a few minutes, compared to 2 days for analysis by ATR-FT-IR. NEMS-IR constitutes a promising technique for the fast analysis of ENMs.
| Original language | English |
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| Title of host publication | Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Number of pages | 2 |
| Publication date | 2014 |
| Pages | 2552-2553 |
| Publication status | Published - 2014 |
| Event | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences - San Antonio, United States Duration: 26 Oct 2014 → 30 Oct 2014 Conference number: 18 https://microtasconferences.org/microtas2014/ |
Conference
| Conference | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|---|
| Number | 18 |
| Country/Territory | United States |
| City | San Antonio |
| Period | 26/10/2014 → 30/10/2014 |
| Internet address |
Keywords
- NEMS-IR
- Engineered nanoparticles
- Nanomedicine
- Infrared spectroscopy