Nanofibrous nonwovens based on dendritic-linear-dendritic poly(ethylene glycol) hybrids

Stefanos Kikionis, Efstathia Ioannou, Oliver C.J. Andren, Ioannis S. Chronakis, Amir Fahmi, Michael Malkoch, Georgios Toskas, Vassilios Roussis

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Dendritic-linear-dendritic (DLD) hybrids are highly functional materials combining the properties of linear and dendritic polymers. Attempts to electrospin DLD polymers composed of hyperbranched dendritic blocks of 2,2-bis(hydroxymethyl) propionic acid on a linear poly(ethylene glycol) core proved unsuccessful. Nevertheless, when these DLD hybrids were blended with an array of different biodegradable polymers as entanglement enhancers, nanofibrous nonwovens were successfully prepared by electrospinning. The pseudogeneration degree of the DLDs, the nature of the co-electrospun polymer and the solvent systems used for the preparation of the electrospinning solutions exerted a significant effect on the diameter and morphology of the electrospun fibers. It is worth-noting that aqueous solutions of the DLD polymers and only 1% (w/v) poly(ethylene oxide) resulted in the production of smoother and thinner nanofibers. Such dendritic nanofibrous scaffolds can be promising materials for biomedical applications due to their biocompatibility, biodegradability, multifunctionality, and advanced structural architecture.
Original languageEnglish
Article number45949
JournalJournal of Applied Polymer Science
Volume135
Issue number10
Number of pages13
ISSN0021-8995
DOIs
Publication statusPublished - 2017

Keywords

  • Chemistry (all)
  • Surfaces, Coatings and Films
  • Polymers and Plastics
  • Materials Chemistry
  • Biodegradable
  • Dendrimers
  • Electrospinning
  • Fibers
  • Hyperbranched polymers and macrocycles
  • Biocompatibility
  • Biodegradability
  • Biodegradable polymers
  • Ethylene
  • Ethylene glycol
  • Functional materials
  • Medical applications
  • Nanofibers
  • Polyethylene glycols
  • Polyethylene oxides
  • Polyols
  • Propionic acid
  • Scaffolds
  • Scaffolds (biology)
  • Solutions
  • Spinning (fibers)
  • Weaving
  • Biomedical applications
  • Electrospun fibers
  • Linear dendritic
  • Macrocycles
  • Multifunctionality
  • Nanofibrous scaffolds
  • Structural architecture

Cite this

Kikionis, S., Ioannou, E., Andren, O. C. J., Chronakis, I. S., Fahmi, A., Malkoch, M., ... Roussis, V. (2017). Nanofibrous nonwovens based on dendritic-linear-dendritic poly(ethylene glycol) hybrids. Journal of Applied Polymer Science, 135(10), [45949]. https://doi.org/10.1002/app.45949
Kikionis, Stefanos ; Ioannou, Efstathia ; Andren, Oliver C.J. ; Chronakis, Ioannis S. ; Fahmi, Amir ; Malkoch, Michael ; Toskas, Georgios ; Roussis, Vassilios. / Nanofibrous nonwovens based on dendritic-linear-dendritic poly(ethylene glycol) hybrids. In: Journal of Applied Polymer Science. 2017 ; Vol. 135, No. 10.
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abstract = "Dendritic-linear-dendritic (DLD) hybrids are highly functional materials combining the properties of linear and dendritic polymers. Attempts to electrospin DLD polymers composed of hyperbranched dendritic blocks of 2,2-bis(hydroxymethyl) propionic acid on a linear poly(ethylene glycol) core proved unsuccessful. Nevertheless, when these DLD hybrids were blended with an array of different biodegradable polymers as entanglement enhancers, nanofibrous nonwovens were successfully prepared by electrospinning. The pseudogeneration degree of the DLDs, the nature of the co-electrospun polymer and the solvent systems used for the preparation of the electrospinning solutions exerted a significant effect on the diameter and morphology of the electrospun fibers. It is worth-noting that aqueous solutions of the DLD polymers and only 1{\%} (w/v) poly(ethylene oxide) resulted in the production of smoother and thinner nanofibers. Such dendritic nanofibrous scaffolds can be promising materials for biomedical applications due to their biocompatibility, biodegradability, multifunctionality, and advanced structural architecture.",
keywords = "Chemistry (all), Surfaces, Coatings and Films, Polymers and Plastics, Materials Chemistry, Biodegradable, Dendrimers, Electrospinning, Fibers, Hyperbranched polymers and macrocycles, Biocompatibility, Biodegradability, Biodegradable polymers, Ethylene, Ethylene glycol, Functional materials, Medical applications, Nanofibers, Polyethylene glycols, Polyethylene oxides, Polyols, Propionic acid, Scaffolds, Scaffolds (biology), Solutions, Spinning (fibers), Weaving, Biomedical applications, Electrospun fibers, Linear dendritic, Macrocycles, Multifunctionality, Nanofibrous scaffolds, Structural architecture",
author = "Stefanos Kikionis and Efstathia Ioannou and Andren, {Oliver C.J.} and Chronakis, {Ioannis S.} and Amir Fahmi and Michael Malkoch and Georgios Toskas and Vassilios Roussis",
year = "2017",
doi = "10.1002/app.45949",
language = "English",
volume = "135",
journal = "Journal of Applied Polymer Science",
issn = "0021-8995",
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Kikionis, S, Ioannou, E, Andren, OCJ, Chronakis, IS, Fahmi, A, Malkoch, M, Toskas, G & Roussis, V 2017, 'Nanofibrous nonwovens based on dendritic-linear-dendritic poly(ethylene glycol) hybrids', Journal of Applied Polymer Science, vol. 135, no. 10, 45949. https://doi.org/10.1002/app.45949

Nanofibrous nonwovens based on dendritic-linear-dendritic poly(ethylene glycol) hybrids. / Kikionis, Stefanos; Ioannou, Efstathia; Andren, Oliver C.J.; Chronakis, Ioannis S.; Fahmi, Amir; Malkoch, Michael; Toskas, Georgios; Roussis, Vassilios.

In: Journal of Applied Polymer Science, Vol. 135, No. 10, 45949, 2017.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Nanofibrous nonwovens based on dendritic-linear-dendritic poly(ethylene glycol) hybrids

AU - Kikionis, Stefanos

AU - Ioannou, Efstathia

AU - Andren, Oliver C.J.

AU - Chronakis, Ioannis S.

AU - Fahmi, Amir

AU - Malkoch, Michael

AU - Toskas, Georgios

AU - Roussis, Vassilios

PY - 2017

Y1 - 2017

N2 - Dendritic-linear-dendritic (DLD) hybrids are highly functional materials combining the properties of linear and dendritic polymers. Attempts to electrospin DLD polymers composed of hyperbranched dendritic blocks of 2,2-bis(hydroxymethyl) propionic acid on a linear poly(ethylene glycol) core proved unsuccessful. Nevertheless, when these DLD hybrids were blended with an array of different biodegradable polymers as entanglement enhancers, nanofibrous nonwovens were successfully prepared by electrospinning. The pseudogeneration degree of the DLDs, the nature of the co-electrospun polymer and the solvent systems used for the preparation of the electrospinning solutions exerted a significant effect on the diameter and morphology of the electrospun fibers. It is worth-noting that aqueous solutions of the DLD polymers and only 1% (w/v) poly(ethylene oxide) resulted in the production of smoother and thinner nanofibers. Such dendritic nanofibrous scaffolds can be promising materials for biomedical applications due to their biocompatibility, biodegradability, multifunctionality, and advanced structural architecture.

AB - Dendritic-linear-dendritic (DLD) hybrids are highly functional materials combining the properties of linear and dendritic polymers. Attempts to electrospin DLD polymers composed of hyperbranched dendritic blocks of 2,2-bis(hydroxymethyl) propionic acid on a linear poly(ethylene glycol) core proved unsuccessful. Nevertheless, when these DLD hybrids were blended with an array of different biodegradable polymers as entanglement enhancers, nanofibrous nonwovens were successfully prepared by electrospinning. The pseudogeneration degree of the DLDs, the nature of the co-electrospun polymer and the solvent systems used for the preparation of the electrospinning solutions exerted a significant effect on the diameter and morphology of the electrospun fibers. It is worth-noting that aqueous solutions of the DLD polymers and only 1% (w/v) poly(ethylene oxide) resulted in the production of smoother and thinner nanofibers. Such dendritic nanofibrous scaffolds can be promising materials for biomedical applications due to their biocompatibility, biodegradability, multifunctionality, and advanced structural architecture.

KW - Chemistry (all)

KW - Surfaces, Coatings and Films

KW - Polymers and Plastics

KW - Materials Chemistry

KW - Biodegradable

KW - Dendrimers

KW - Electrospinning

KW - Fibers

KW - Hyperbranched polymers and macrocycles

KW - Biocompatibility

KW - Biodegradability

KW - Biodegradable polymers

KW - Ethylene

KW - Ethylene glycol

KW - Functional materials

KW - Medical applications

KW - Nanofibers

KW - Polyethylene glycols

KW - Polyethylene oxides

KW - Polyols

KW - Propionic acid

KW - Scaffolds

KW - Scaffolds (biology)

KW - Solutions

KW - Spinning (fibers)

KW - Weaving

KW - Biomedical applications

KW - Electrospun fibers

KW - Linear dendritic

KW - Macrocycles

KW - Multifunctionality

KW - Nanofibrous scaffolds

KW - Structural architecture

U2 - 10.1002/app.45949

DO - 10.1002/app.45949

M3 - Journal article

VL - 135

JO - Journal of Applied Polymer Science

JF - Journal of Applied Polymer Science

SN - 0021-8995

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M1 - 45949

ER -