This work presents new experimental phase equilibrium data of binary MEG-reservoir fluid and ternary MEG-water-reservoir fluid systems at temperatures 275-326 K and at atmospheric pressure. The reservoir fluid consists of a natural gas condensate from a Statoil operated gas field in the North Sea. Prediction of mutual solubility of water, MEG and hydrocarbon fluids is important for the oil industry to ensure production and processing as well as to satisfy environmental regulations. The CPA equation of state has been successfully applied in the past to well defined systems containing associating compounds. It has also been extended to reservoir fluids in presence of water and polar chemicals using a Pedersen like characterization method with modified correlations for critical temperature, pressure and acentric factor. In this work CPA is applied to the prediction of mutual solubility of reservoir fluid and polar compounds such as water and MEG. Satisfactory results are obtained for mutual solubility of MEG and gas condensate whereas some deviations are observed for the ternary system of MEG-water-gas condensate.