Muscle growth is reduced in 15-month-old children with cerebral palsy

Anna Herskind, Anina Ritterband-Rosenbaum, Maria Willerslev-Olsen, Jakob Lorentzen, Lars G. Hanson, Glen Lichtwark, Jens B. Nielsen

Research output: Contribution to journalJournal articleResearchpeer-review


AimLack of muscle growth relative to bone growth may be responsible for development of contractures in children with cerebral palsy (CP). Here, we used ultrasonography to compare growth of the medial gastrocnemius muscle in children with and without CP.MethodTwenty-six children with spastic CP (15 males, 11 females; mean age 35mo, range 8-65mo) and 101 typically developing children (47 males, 54 females; mean age 29mo, range 1-69mo) were included. Functional abilities of children with CP equalled levels I to III in the Gross Motor Function Classification System. Medial gastrocnemius muscle volume was constructed from serial, transverse, two-dimensional ultrasonography images.ResultsIn typically developing children, medial gastrocnemius volume increased linearly with age. Among children with CP, medial gastrocnemius volume increased less with age and deviated significantly from typically developing children at 15 months of age (p
Original languageEnglish
JournalDevelopmental Medicine and Child Neurology
Issue number5
Pages (from-to)485-491
Publication statusPublished - 2016


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