Multiplexed optical coherence tomography imaging of optic disc drusen

Optic disc drusen (ODD) are calcified masses in the prelaminar optic nerve head seen in up to 2% of the population. Although the pathophysiology is not fully understood, altered microvascularization could both be part of the pathogenesis and a consequence of ODD.[1] We developed a method that combines information from optical coherence tomography (OCT) angiography regarding peripapillary vessel density along with information from enhanced depth imaging OCT about anatomical ODD location and volume [Fig. 1]. In this patient, the majority of the ODD volume is located nasally and in the adjacent peripapillary section wherein the vessel
density is correspondingly lower.