Abstract
The present invention relates to a multiplex editing system. The system allows multiple editing of nucleic acid sequences such as genomic sequences, such as knockins of genes of interest in a genome, knockouts of genomic sequences and/or allele replacement. Also provided herein are a method for editing nucleic acids and a cell comprising a stably integrated endonuclease.
| Original language | English |
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| IPC | C12N15/102; C12N15/902; C12N9/22 |
| Patent number | WO2015052231 |
| Filing date | 16/04/2016 |
| Country/Territory | International Bureau of the World Intellectual Property Organization (WIPO) |
| Priority date | 08/10/2013 |
| Priority number | EP20130187681 |
| Publication status | Published - 16 Apr 2015 |