Multi-Stimuli-Responsive Polymer Particles, Films, and Hydrogels for Drug Delivery

Xiao Fu, Leticia Hosta-Rigau*, Rona Chandrawati, Jiwei Cui

*Corresponding author for this work

    Research output: Contribution to journalReviewResearchpeer-review

    Abstract

    Stimuli-responsive polymermaterials are powerful tools in drug delivery and tissue engineering. Because of the large variations in physiological conditions between normal microenvironments and diseased sites, polymer materials with single responsiveness may not achieve the desired goals in a complex physiological microenvironment. Instead, polymer materials responsive to multiple physical or chemical stimuli are highly desired for biomedical applications (e.g., drug delivery). In this review, we highlight recent studies in multi-stimuli-responsive materials with a specific emphasis on polymer particles, films, and hydrogels. The synthetic strategies employed to produce these responsive materials are described. Applications in drug delivery are highlighted, followed by a discussion of the current research focus and future trends.
    Original languageEnglish
    JournalChem
    Volume4
    Issue number9
    Pages (from-to)2084-2107
    ISSN2451-9294
    DOIs
    Publication statusPublished - 2018

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