Mucispirillum schaedleri gen. nov., sp nov., a spiral-shaped bacterium colonizing the mucus layer of the gastrointestinal tract of laboratory rodents

B.R. Robertson, J.L. O'Rourke, B.A. Neilan, P. Vandamme, Stephen L. W. On, J.G. Fox, A. Lee

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    The mammalian gastrointestinal tract is covered by a layer of mucus that can harbour a range of bacterial species specifically adapted to colonize this ecological niche. Examination of 110 bacterial isolates cultivated from the gastrointestinal tract of 23 mice revealed the presence of a subgroup of 30 isolates that did not correspond genetically with genera commonly associated with this site, i.e. members of the epsilon-Proteobacteria such as Helicobacter and Campylobacter species. Instead this group of isolates was found to lie within the phylum Deferribacteres, a completely distinct lineage in the domain Bacteria. There was a high level of consensus in results obtained from the phenotypic and genotypic characterization of a number of the isolates, which showed they were distinct from other members of the Deferribacteres. As such, they are proposed to constitute a new genus and species, Mucispirillum schaedleri gen. nov., sp. nov. These organisms are anaerobic, Gram-negative, spiral-shaped rods with bipolar flagella. The type strain is HRI 117(T) (=ATCC BAA-1009(T) = ACM 5223(T)).
    Original languageEnglish
    JournalInternational Journal of Systematic and Evolutionary Microbiology
    Volume55
    Issue number3
    Pages (from-to)1199-1204
    ISSN1466-5026
    DOIs
    Publication statusPublished - 2005

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