Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study

Nerea Mangado Lopez; Mario Ceresa; Hector Dejea Velardo; Hans Martin Kjer; Sergio Vera; Rasmus Reinhold Paulsen; Jens Fagertun; Pavel Mistrik; Gemma Piella; Miguel Angel González Ballester

doi:10.1007/978-3-319-31808-0_12

Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study

Nerea Mangado Lopez
, Mario Ceresa
, Hector Dejea Velardo
, Hans Martin Kjer
, Sergio Vera
, Rasmus Reinhold Paulsen
, Jens Fagertun
, Pavel Mistrik
, Gemma Piella
, Miguel Angel González Ballester

MED-EL GmbH
Pompeu Fabra University
Alma Medical Systems

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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Abstract

Cochlear implantation is carried out to recover the sense of hearing. However, its functional outcome varies highly between patients. In the current work, we present a study to assess the functional outcomes of cochlear implants considering the inter-variability found among a population of patients. In order to capture the cochlear anatomical details, a statistical shape model is created from high-resolution human μCT data. A population of virtual patients is automatically generated by sampling new anatomical instances from the statistical shape model. For each virtual patient, an implant insertion is simulated and a finite element model is generated to estimate the electrical field created into the cochlea. These simulations are defined according to the monopolar stimulation protocol of a cochlear implant and a prediction of the voltage spread over the population of virtual patients is evaluated.

Original language	English
Title of host publication	Revised Selected Papers of the 4th International Workshop Clinical Image-Based Procedures: Translational Research in Medical Imaging (CLIP 2015)
Publisher	Springer
Publication date	2016
Pages	96-103
ISBN (Print)	978-3-319-31807-3
ISBN (Electronic)	978-3-319-31808-0
DOIs	https://doi.org/10.1007/978-3-319-31808-0_12
Publication status	Published - 2016
Event	4th Workshop on Clinical Image-based Procedures (CLIP 2015): Translational Research in Medical Imaging - Munich, Germany Duration: 5 Oct 2015 → 5 Oct 2015 Conference number: 4 http://miccai-clip.org/2015/

Workshop

Workshop	4th Workshop on Clinical Image-based Procedures (CLIP 2015)
Number	4
Country/Territory	Germany
City	Munich
Period	05/10/2015 → 05/10/2015
Other	Held in Conjunction with MICCAI 2015
Internet address	http://miccai-clip.org/2015/

Series	Lecture Notes in Computer Science
Volume	9401
ISSN	0302-9743

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Mangado Lopez, N., Ceresa, M., Dejea Velardo, H., Kjer, H. M., Vera, S., Paulsen, R. R., Fagertun, J., Mistrik, P., Piella, G., & González Ballester, M. A. (2016). Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study. In Revised Selected Papers of the 4th International Workshop Clinical Image-Based Procedures: Translational Research in Medical Imaging (CLIP 2015) (pp. 96-103). Springer. https://doi.org/10.1007/978-3-319-31808-0_12

Mangado Lopez, Nerea ; Ceresa, Mario ; Dejea Velardo, Hector et al. / Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study. Revised Selected Papers of the 4th International Workshop Clinical Image-Based Procedures: Translational Research in Medical Imaging (CLIP 2015). Springer, 2016. pp. 96-103 (Lecture Notes in Computer Science, Vol. 9401).

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title = "Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study",

abstract = "Cochlear implantation is carried out to recover the sense of hearing. However, its functional outcome varies highly between patients. In the current work, we present a study to assess the functional outcomes of cochlear implants considering the inter-variability found among a population of patients. In order to capture the cochlear anatomical details, a statistical shape model is created from high-resolution human μCT data. A population of virtual patients is automatically generated by sampling new anatomical instances from the statistical shape model. For each virtual patient, an implant insertion is simulated and a finite element model is generated to estimate the electrical field created into the cochlea. These simulations are defined according to the monopolar stimulation protocol of a cochlear implant and a prediction of the voltage spread over the population of virtual patients is evaluated.",

author = "\{Mangado Lopez\}, Nerea and Mario Ceresa and \{Dejea Velardo\}, Hector and Kjer, \{Hans Martin\} and Sergio Vera and Paulsen, \{Rasmus Reinhold\} and Jens Fagertun and Pavel Mistrik and Gemma Piella and \{Gonz{\'a}lez Ballester\}, \{Miguel Angel\}",

year = "2016",

doi = "10.1007/978-3-319-31808-0\_12",

language = "English",

isbn = " 978-3-319-31807-3 ",

series = "Lecture Notes in Computer Science",

publisher = "Springer",

pages = "96--103",

booktitle = "Revised Selected Papers of the 4th International Workshop Clinical Image-Based Procedures: Translational Research in Medical Imaging (CLIP 2015)",

note = "4th Workshop on Clinical Image-based Procedures (CLIP 2015) : Translational Research in Medical Imaging, CLIP ; Conference date: 05-10-2015 Through 05-10-2015",

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}

Mangado Lopez, N, Ceresa, M, Dejea Velardo, H, Kjer, HM, Vera, S, Paulsen, RR, Fagertun, J, Mistrik, P, Piella, G & González Ballester, MA 2016, Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study. in Revised Selected Papers of the 4th International Workshop Clinical Image-Based Procedures: Translational Research in Medical Imaging (CLIP 2015). Springer, Lecture Notes in Computer Science, vol. 9401, pp. 96-103, 4th Workshop on Clinical Image-based Procedures (CLIP 2015), Munich, Germany, 05/10/2015. https://doi.org/10.1007/978-3-319-31808-0_12

Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study. / Mangado Lopez, Nerea; Ceresa, Mario; Dejea Velardo, Hector et al.
Revised Selected Papers of the 4th International Workshop Clinical Image-Based Procedures: Translational Research in Medical Imaging (CLIP 2015). Springer, 2016. p. 96-103 (Lecture Notes in Computer Science, Vol. 9401).

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

TY - GEN

T1 - Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study

AU - Mangado Lopez, Nerea

AU - Ceresa, Mario

AU - Dejea Velardo, Hector

AU - Kjer, Hans Martin

AU - Vera, Sergio

AU - Paulsen, Rasmus Reinhold

AU - Fagertun, Jens

AU - Mistrik, Pavel

AU - Piella, Gemma

AU - González Ballester, Miguel Angel

N1 - Conference code: 4

PY - 2016

Y1 - 2016

N2 - Cochlear implantation is carried out to recover the sense of hearing. However, its functional outcome varies highly between patients. In the current work, we present a study to assess the functional outcomes of cochlear implants considering the inter-variability found among a population of patients. In order to capture the cochlear anatomical details, a statistical shape model is created from high-resolution human μCT data. A population of virtual patients is automatically generated by sampling new anatomical instances from the statistical shape model. For each virtual patient, an implant insertion is simulated and a finite element model is generated to estimate the electrical field created into the cochlea. These simulations are defined according to the monopolar stimulation protocol of a cochlear implant and a prediction of the voltage spread over the population of virtual patients is evaluated.

AB - Cochlear implantation is carried out to recover the sense of hearing. However, its functional outcome varies highly between patients. In the current work, we present a study to assess the functional outcomes of cochlear implants considering the inter-variability found among a population of patients. In order to capture the cochlear anatomical details, a statistical shape model is created from high-resolution human μCT data. A population of virtual patients is automatically generated by sampling new anatomical instances from the statistical shape model. For each virtual patient, an implant insertion is simulated and a finite element model is generated to estimate the electrical field created into the cochlea. These simulations are defined according to the monopolar stimulation protocol of a cochlear implant and a prediction of the voltage spread over the population of virtual patients is evaluated.

U2 - 10.1007/978-3-319-31808-0_12

DO - 10.1007/978-3-319-31808-0_12

M3 - Article in proceedings

SN - 978-3-319-31807-3

T3 - Lecture Notes in Computer Science

SP - 96

EP - 103

BT - Revised Selected Papers of the 4th International Workshop Clinical Image-Based Procedures: Translational Research in Medical Imaging (CLIP 2015)

PB - Springer

T2 - 4th Workshop on Clinical Image-based Procedures (CLIP 2015)

Y2 - 5 October 2015 through 5 October 2015

ER -

Mangado Lopez N, Ceresa M, Dejea Velardo H, Kjer HM, Vera S, Paulsen RR et al. Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study. In Revised Selected Papers of the 4th International Workshop Clinical Image-Based Procedures: Translational Research in Medical Imaging (CLIP 2015). Springer. 2016. p. 96-103. (Lecture Notes in Computer Science, Vol. 9401). doi: 10.1007/978-3-319-31808-0_12

Monopolar Stimulation of the Implanted Cochlea: A Synthetic Population-Based Study

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