Abstract
This perspective article is based on an expert panel review on microbioreactor applications in biochemical
and biomedical engineering that was organized by the M3C (measurement, monitoring, modelling and control) Working Group of the European Section of Biochemical Engineering Science (ESBES) in the European Federation of Biotechnology (EFB). The aim of the panel was to provide an updated view on the present status of the subject and to identify critical needs and issues for furthering the successful development of microbioreactor monitoring and control. This will benefit future bioprocess development and in vitro toxicity testing. The article concludes with a set
of recommendations for extended use and further development of microbioreactors.
and biomedical engineering that was organized by the M3C (measurement, monitoring, modelling and control) Working Group of the European Section of Biochemical Engineering Science (ESBES) in the European Federation of Biotechnology (EFB). The aim of the panel was to provide an updated view on the present status of the subject and to identify critical needs and issues for furthering the successful development of microbioreactor monitoring and control. This will benefit future bioprocess development and in vitro toxicity testing. The article concludes with a set
of recommendations for extended use and further development of microbioreactors.
| Original language | English |
|---|---|
| Journal | Biotechnology Journal |
| Volume | 7 |
| Issue number | 10 |
| Pages (from-to) | 1308-1314 |
| ISSN | 1860-6768 |
| DOIs | |
| Publication status | Published - 2012 |
Keywords
- Bioreactor control
- High-throughput screening
- In vitro testing
- Microfluidics
- On-line monitoring