Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

Xiaotong Feng; Jon Ashley; Tongchang Zhou; Arnab Halder; Yi Sun

doi:10.1039/c8an00711j

Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

Xiaotong Feng, Jon Ashley, Tongchang Zhou, Arnab Halder, Yi Sun^*

^*Corresponding author for this work

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Abstract

Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.

Original language	English
Journal	Analyst
Volume	143
Issue number	12
Pages (from-to)	2750-2754
ISSN	0003-2654
DOIs	https://doi.org/10.1039/c8an00711j
Publication status	Published - 2018

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title = "Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction",

abstract = "Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.",

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AU - Feng, Xiaotong

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AU - Zhou, Tongchang

AU - Halder, Arnab

AU - Sun, Yi

PY - 2018

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AB - Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.

U2 - 10.1039/c8an00711j

DO - 10.1039/c8an00711j

M3 - Journal article

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SN - 0003-2654

VL - 143

SP - 2750

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JO - Analyst

JF - Analyst

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ER -

Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction

Abstract

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