TY - JOUR
T1 - Molecular Recognition in NADPH-Dependent Plant Thioredoxin Systems-Catalytic Mechanisms, Structural Snapshots and Target Identifications
AU - Hägglund, Per
AU - Kirkensgaard, Kristine Groth
AU - Maeda, Kenji
AU - Finnie, Christine
AU - Henriksen, Anette
AU - Svensson, Birte
PY - 2009
Y1 - 2009
N2 - NADPH-dependent thioredoxin Systems (NTS) control enzymatic activities and provide reducing equivalents to metabolic pathways in all types of organisms. from bacteria to mammals In these redox systems, thioredoxin reduces disulfide bonds in target proteins and receives electrons from NADPH via thioredoxin reductase (NTR). Plant NTS were first discovered in wheat seeds some 30 years ago and were demonstrated to play a key role in the seed germination process Since then, NTS have been identified in a large. variety of photosynthetic organisms. and,in organelle-specific pattern for their cellular localization is established The last decade has witnessed a remarkable expansion of the knowledge about these systems and novel molecular architectures. catalytic mechanisms and target proteins have been revealed. In general, these findings have provided a wealth of information about the physiological role and molecular mechanisms of plant NTS, and this chapter will highlight some of the recent developments in this area
AB - NADPH-dependent thioredoxin Systems (NTS) control enzymatic activities and provide reducing equivalents to metabolic pathways in all types of organisms. from bacteria to mammals In these redox systems, thioredoxin reduces disulfide bonds in target proteins and receives electrons from NADPH via thioredoxin reductase (NTR). Plant NTS were first discovered in wheat seeds some 30 years ago and were demonstrated to play a key role in the seed germination process Since then, NTS have been identified in a large. variety of photosynthetic organisms. and,in organelle-specific pattern for their cellular localization is established The last decade has witnessed a remarkable expansion of the knowledge about these systems and novel molecular architectures. catalytic mechanisms and target proteins have been revealed. In general, these findings have provided a wealth of information about the physiological role and molecular mechanisms of plant NTS, and this chapter will highlight some of the recent developments in this area
U2 - 10.1016/S0065-2296(10)52015-9
DO - 10.1016/S0065-2296(10)52015-9
M3 - Review
SN - 0065-2296
VL - 52
SP - 461
EP - 495
JO - Advances in Botanical Research
JF - Advances in Botanical Research
ER -