Modelling continuous pharmaceutical and bio-based processes at plant-wide level: A roadmap towards efficient decision-making

The importance of developing simulation models for decision making in pharmaceutical and bio-based production processes is elaborated in this article. The advantages of modelling continuous processes are outlined and certain barriers in this regard are identified. Although there have been some advancements in the field, there needs to be a larger international collaboration in this regard for providing reliable data for model validation, for development of generic modelbased frameworks and implementing them in computer-aided platforms in the form of software tools.