Mixed effect modeling of tetracycline resistance levels in Danish slaughter pigs

Elisabeth Ottesen Bangsgaard; Kaare Græsbøll; Vibe Dalhoff Andersen; Julie Clasen; Dziuginta Jasinskyt; Julie Elvekjær Hansen; Anders Folkesson; Lasse Engbo Christiansen

doi:10.1016/j.prevetmed.2021.105362

Mixed effect modeling of tetracycline resistance levels in Danish slaughter pigs

Elisabeth Ottesen Bangsgaard^*, Kaare Græsbøll, Vibe Dalhoff Andersen, Julie Clasen, Dziuginta Jasinskyt, Julie Elvekjær Hansen, Anders Folkesson, Lasse Engbo Christiansen

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Mathematical and statistical modeling can be a very useful tool in understanding and fighting antimicrobial resistance (AMR). Here we present investigations of mixed effect models of varying complexity in order to identify and address possible management factors affecting the tetracycline AMR levels in Danish pig farms. Besides antimicrobial exposure during pigs life cycle, the type of production seems to also have an influence. The results concludes that not only fully integrated farms (CHR integrated) but also farms in a production network with a single ownership (CVR integrated) might have a preventive effect on levels of tetracycline AMR compared to more complex trading patterns.

Original language	English
Article number	105362
Journal	Preventive Veterinary Medicine
Volume	191
ISSN	0167-5877
DOIs	https://doi.org/10.1016/j.prevetmed.2021.105362
Publication status	Published - 2021

Keywords

Antimicrobial resistance
Tetracycline
Danish pig production
Mixed effect modeling

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title = "Mixed effect modeling of tetracycline resistance levels in Danish slaughter pigs",

abstract = "Mathematical and statistical modeling can be a very useful tool in understanding and fighting antimicrobial resistance (AMR). Here we present investigations of mixed effect models of varying complexity in order to identify and address possible management factors affecting the tetracycline AMR levels in Danish pig farms. Besides antimicrobial exposure during pigs life cycle, the type of production seems to also have an influence. The results concludes that not only fully integrated farms (CHR integrated) but also farms in a production network with a single ownership (CVR integrated) might have a preventive effect on levels of tetracycline AMR compared to more complex trading patterns.",

keywords = "Antimicrobial resistance, Tetracycline, Danish pig production, Mixed effect modeling",

author = "Bangsgaard, {Elisabeth Ottesen} and Kaare Gr{\ae}sb{\o}ll and {Dalhoff Andersen}, Vibe and Julie Clasen and Dziuginta Jasinskyt and Hansen, {Julie Elvekj{\ae}r} and Anders Folkesson and Christiansen, {Lasse Engbo}",

year = "2021",

doi = "10.1016/j.prevetmed.2021.105362",

language = "English",

volume = "191",

journal = "Preventive Veterinary Medicine",

issn = "0167-5877",

publisher = "Elsevier",

}

Mixed effect modeling of tetracycline resistance levels in Danish slaughter pigs. / Bangsgaard, Elisabeth Ottesen ; Græsbøll, Kaare ; Dalhoff Andersen, Vibe; Clasen, Julie; Jasinskyt, Dziuginta; Hansen, Julie Elvekjær; Folkesson, Anders; Christiansen, Lasse Engbo.

In: Preventive Veterinary Medicine, Vol. 191, 105362, 2021.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Mixed effect modeling of tetracycline resistance levels in Danish slaughter pigs

AU - Bangsgaard, Elisabeth Ottesen

AU - Græsbøll, Kaare

AU - Dalhoff Andersen, Vibe

AU - Clasen, Julie

AU - Jasinskyt, Dziuginta

AU - Hansen, Julie Elvekjær

AU - Folkesson, Anders

AU - Christiansen, Lasse Engbo

PY - 2021

Y1 - 2021

N2 - Mathematical and statistical modeling can be a very useful tool in understanding and fighting antimicrobial resistance (AMR). Here we present investigations of mixed effect models of varying complexity in order to identify and address possible management factors affecting the tetracycline AMR levels in Danish pig farms. Besides antimicrobial exposure during pigs life cycle, the type of production seems to also have an influence. The results concludes that not only fully integrated farms (CHR integrated) but also farms in a production network with a single ownership (CVR integrated) might have a preventive effect on levels of tetracycline AMR compared to more complex trading patterns.

AB - Mathematical and statistical modeling can be a very useful tool in understanding and fighting antimicrobial resistance (AMR). Here we present investigations of mixed effect models of varying complexity in order to identify and address possible management factors affecting the tetracycline AMR levels in Danish pig farms. Besides antimicrobial exposure during pigs life cycle, the type of production seems to also have an influence. The results concludes that not only fully integrated farms (CHR integrated) but also farms in a production network with a single ownership (CVR integrated) might have a preventive effect on levels of tetracycline AMR compared to more complex trading patterns.

KW - Antimicrobial resistance

KW - Tetracycline

KW - Danish pig production

KW - Mixed effect modeling

U2 - 10.1016/j.prevetmed.2021.105362

DO - 10.1016/j.prevetmed.2021.105362

M3 - Journal article

VL - 191

JO - Preventive Veterinary Medicine

JF - Preventive Veterinary Medicine

SN - 0167-5877

M1 - 105362

ER -