TY - JOUR
T1 - Miniaturized tools and devices for bioanalytical applications: an overview
AU - Chudy, M.
AU - Grabowska, I.
AU - Ciosek, P.
AU - Filipowicz-Szymanska, A.
AU - Stadnik, D.
AU - Wyzkiewicz, I.
AU - Jedrych, E.
AU - Juchniewicz, M.
AU - Skolimowski, Maciej
AU - Ziolkowska, K.
AU - Kwapiszewski, R.
PY - 2009
Y1 - 2009
N2 - This article presents an overview of various miniaturized devices and technologies developed by our group. Innovative, fast and cheap procedures for the fabrication of laboratory microsystems based on commercially available materials are reported and compared with well-established microfabrication techniques. The modules fabricated and tested in our laboratory can be used independently or they can be set up in different configurations to form functional measurement systems. We also report further applications of the presented modules e.g. disposable poly(dimethylsiloxane) (PDMS) microcuvettes, fibre optic detectors, potentiometric sensors platforms, microreactors and capillary electrophoresis (CE) microchips as well as integrated microsystems e. g. double detection microanalytical systems, devices for studying enzymatic reactions and a microsystem for cell culture and lysis.
AB - This article presents an overview of various miniaturized devices and technologies developed by our group. Innovative, fast and cheap procedures for the fabrication of laboratory microsystems based on commercially available materials are reported and compared with well-established microfabrication techniques. The modules fabricated and tested in our laboratory can be used independently or they can be set up in different configurations to form functional measurement systems. We also report further applications of the presented modules e.g. disposable poly(dimethylsiloxane) (PDMS) microcuvettes, fibre optic detectors, potentiometric sensors platforms, microreactors and capillary electrophoresis (CE) microchips as well as integrated microsystems e. g. double detection microanalytical systems, devices for studying enzymatic reactions and a microsystem for cell culture and lysis.
KW - Bonding-less (b-less) and pull-out techniques
KW - Capillary film
KW - Cell culture passage and lysis
KW - Dual detection
KW - Enzymatic microreactors
KW - Microchips for capillary electrophoresis (MCE)
U2 - 10.1007/s00216-009-2979-2
DO - 10.1007/s00216-009-2979-2
M3 - Journal article
C2 - 19649753
SN - 1618-2642
VL - 395
SP - 647
EP - 668
JO - Analytical and Bioanalytical Chemistry
JF - Analytical and Bioanalytical Chemistry
IS - 3
ER -