Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded lab-on-a-chip

Tran Quang Hung, Yi Sun, Carl Esben Poulsen, Quyen Than Linh, Wai Hoe Chin, Dang Duong Bang, Anders Wolff

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Abstract

A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.
Original languageEnglish
JournalLab on a Chip
Volume15
Issue number11
Pages (from-to)2445-2451
ISSN1473-0197
DOIs
Publication statusPublished - 2015

Bibliographical note

© The Royal Society of Chemistry 2015

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