Abstract
A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.
Original language | English |
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Journal | Lab on a Chip |
Volume | 15 |
Issue number | 11 |
Pages (from-to) | 2445-2451 |
ISSN | 1473-0197 |
DOIs | |
Publication status | Published - 2015 |