Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber

Christian Rosenberg Petersen (Invited author), Nikola Prtljaga (Invited author), Mark Farries (Invited author), Jon Ward (Invited author), Bruce Napier (Invited author), Gavin Rhys Lloyd (Invited author), Jayakrupakar Nallala (Invited author), Nick Stone (Invited author), Ole Bang (Invited author)

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

628 Downloads (Pure)

Abstract

We present the first demonstration of mid-infrared spectroscopic imaging of human tissue using a fiber-coupled supercontinuum source spanning from 2-7.5 μm. The supercontinuum was generated in a tapered large mode area chalcogenide photonic crystal fiber in order to obtain broad bandwidth, high average power, and single-mode output for good imaging properties. Tissue imaging was demonstrated in transmission by raster scanning over a sub-mm region of paraffinized colon tissue on CaF2 substrate, and the signal was measured using a fiber-coupled grating spectrometer. This demonstration has shown that we can distinguish between epithelial and surrounding connective tissues within a paraffinized section of colon tissue by imaging at discrete wavelengths related to distinct chemical absorption features.
Original languageEnglish
Title of host publicationProceedings of SPIE
Number of pages6
Volume10489
PublisherSPIE - International Society for Optical Engineering
Publication date2018
Article number1048905
DOIs
Publication statusPublished - 2018
EventSPIE Photonics West 2018: SPIE BIOS: Design and Quality for Biomedical Technologies XI -
Duration: 27 Jan 2018 → …

Conference

ConferenceSPIE Photonics West 2018
Period27/01/2018 → …
SeriesProceedings of SPIE, the International Society for Optical Engineering
Volume10489
ISSN0277-786X

Keywords

  • Supercontinuum
  • Spectroscopic imaging
  • Mid-infrared
  • Tissue imaging
  • Chalcogenide optical fibers

Fingerprint

Dive into the research topics of 'Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber'. Together they form a unique fingerprint.

Cite this