Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber

Christian Rosenberg Petersen (Invited author), Nikola Prtljaga (Invited author), Mark Farries (Invited author), Jon Ward (Invited author), Bruce Napier (Invited author), Gavin Rhys Lloyd (Invited author), Jayakrupakar Nallala (Invited author), Nick Stone (Invited author), Ole Bang (Invited author)

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    Abstract

    We present the first demonstration of mid-infrared spectroscopic imaging of human tissue using a fiber-coupled supercontinuum source spanning from 2-7.5 μm. The supercontinuum was generated in a tapered large mode area chalcogenide photonic crystal fiber in order to obtain broad bandwidth, high average power, and single-mode output for good imaging properties. Tissue imaging was demonstrated in transmission by raster scanning over a sub-mm region of paraffinized colon tissue on CaF2 substrate, and the signal was measured using a fiber-coupled grating spectrometer. This demonstration has shown that we can distinguish between epithelial and surrounding connective tissues within a paraffinized section of colon tissue by imaging at discrete wavelengths related to distinct chemical absorption features.
    Original languageEnglish
    Title of host publicationProceedings of SPIE
    Number of pages6
    Volume10489
    PublisherSPIE - International Society for Optical Engineering
    Publication date2018
    Article number1048905
    DOIs
    Publication statusPublished - 2018
    EventSPIE Photonics West 2018: SPIE BIOS: Design and Quality for Biomedical Technologies XI -
    Duration: 27 Jan 2018 → …

    Conference

    ConferenceSPIE Photonics West 2018
    Period27/01/2018 → …
    SeriesProceedings of SPIE, the International Society for Optical Engineering
    Volume10489
    ISSN0277-786X

    Keywords

    • Supercontinuum
    • Spectroscopic imaging
    • Mid-infrared
    • Tissue imaging
    • Chalcogenide optical fibers

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