Microorganisms for the production of melatonin

Eric Michael Knight; Jiangfeng Zhu; Jochen Förster; Hao Luo

Microorganisms for the production of melatonin

Eric Michael Knight (Inventor)
, Jiangfeng Zhu (Inventor)
, Jochen Förster (Inventor)
, Hao Luo (Inventor)

Research output: Patent

364 Downloads (Orbit)

Abstract

Recombinant microbial cells and methods for producing melatonin and related compounds using such cells are described. More specifically, the recombinant microbial cell may comprise exogenous genes encoding one or more of an L-tryptophan hydroxylase, a 5-hydroxy-L- tryptophan decarboxylyase, a serotonin acetyltransferase, an acetylserotonin O- methyltransferase; an L-tryptophan decarboxy-lyase, and a tryptamine-5-hydroxylase, and means for providing tetrahydrobiopterin (THB). Related sequences and vectors for use in preparing such recombinant microbial cells are also described.

Original language	English
IPC	C12N1/21; C12N15/53; C12N15/54
Patent number	WO2013127915
Filing date	06/09/2013
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	29/02/2012
Priority number	EP20120157542
Publication status	Published - 2013

Bibliographical note

Also published as: US2015024440 (A1); EP2820121 (A1)

Access to Document

WO2013127915A1Final published version, 4.36 MB

http://patentscope.wipo.int/search/en/WO2013127915

OpenUrl availability

Check availability in DTU Findit

Cite this

@misc{ccefe80397c042e3b0e184191321a139,

title = "Microorganisms for the production of melatonin",

abstract = "Recombinant microbial cells and methods for producing melatonin and related compounds using such cells are described. More specifically, the recombinant microbial cell may comprise exogenous genes encoding one or more of an L-tryptophan hydroxylase, a 5-hydroxy-L- tryptophan decarboxylyase, a serotonin acetyltransferase, an acetylserotonin O- methyltransferase; an L-tryptophan decarboxy-lyase, and a tryptamine-5-hydroxylase, and means for providing tetrahydrobiopterin (THB). Related sequences and vectors for use in preparing such recombinant microbial cells are also described.",

author = "Knight, \{Eric Michael\} and Jiangfeng Zhu and Jochen F{\"o}rster and Hao Luo",

note = "Also published as: US2015024440 (A1); EP2820121 (A1) ; WO2013127915; C12N1/21; C12N15/53; C12N15/54",

year = "2013",

language = "English",

type = "Patent",

}

TY - PAT

T1 - Microorganisms for the production of melatonin

AU - Knight, Eric Michael

AU - Zhu, Jiangfeng

AU - Förster, Jochen

AU - Luo, Hao

N1 - Also published as: US2015024440 (A1); EP2820121 (A1)

PY - 2013

Y1 - 2013

N2 - Recombinant microbial cells and methods for producing melatonin and related compounds using such cells are described. More specifically, the recombinant microbial cell may comprise exogenous genes encoding one or more of an L-tryptophan hydroxylase, a 5-hydroxy-L- tryptophan decarboxylyase, a serotonin acetyltransferase, an acetylserotonin O- methyltransferase; an L-tryptophan decarboxy-lyase, and a tryptamine-5-hydroxylase, and means for providing tetrahydrobiopterin (THB). Related sequences and vectors for use in preparing such recombinant microbial cells are also described.

AB - Recombinant microbial cells and methods for producing melatonin and related compounds using such cells are described. More specifically, the recombinant microbial cell may comprise exogenous genes encoding one or more of an L-tryptophan hydroxylase, a 5-hydroxy-L- tryptophan decarboxylyase, a serotonin acetyltransferase, an acetylserotonin O- methyltransferase; an L-tryptophan decarboxy-lyase, and a tryptamine-5-hydroxylase, and means for providing tetrahydrobiopterin (THB). Related sequences and vectors for use in preparing such recombinant microbial cells are also described.

M3 - Patent

M1 - WO2013127915

Y2 - 2013/09/06

ER -

Microorganisms for the production of melatonin

Abstract

Bibliographical note

Access to Document

OpenUrl availability

Fingerprint

Cite this