Microorganisms for the production of 5-hydroxytryptophan

Eric Michael Knight (Inventor), Jiangfeng Zhu (Inventor), Jochen Förster (Inventor), Hao Luo (Inventor)

Research output: Patent

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Abstract

Recombinant microbial cells and methods for producing 5-hydroxytryptophan (5HTP) using such cells are described. More specifically, the recombinant microbial cell comprises an exogenous gene encoding an L-tryptophan hydroxylase, and means for providing tetrahydrobiopterin (THB). Related sequences and vectors for use in preparing such recombinant microbial cells are also described.
Original languageEnglish
IPCC12N1/21; C12N15/53; C12N15/55
Patent numberWO2013127914
Filing date06/09/2013
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date29/02/2012
Priority numberEP20120157540
Publication statusPublished - 2013

Bibliographical note

Also published as: US2015037849 (A1); EP2820122 (A1)

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