Recombinant microbial cells and methods for producing 5-hydroxytryptophan (5HTP) using such cells are described. More specifically, the recombinant microbial cell comprises an exogenous gene encoding an L-tryptophan hydroxylase, and means for providing tetrahydrobiopterin (THB). Related sequences and vectors for use in preparing such recombinant microbial cells are also described.
|IPC||C12N1/21; C12N15/53; C12N15/55|
|Country||International Bureau of the World Intellectual Property Organization (WIPO)|
|Publication status||Published - 2013|