Abstract
Recombinant microbial cells and methods for producing 5-hydroxytryptophan (5HTP) using such cells are described. More specifically, the recombinant microbial cell comprises an exogenous gene encoding an L-tryptophan hydroxylase, and means for providing tetrahydrobiopterin (THB). Related sequences and vectors for use in preparing such recombinant microbial cells are also described.
| Original language | English |
|---|---|
| IPC | C12N1/21; C12N15/53; C12N15/55 |
| Patent number | WO2013127914 |
| Filing date | 06/09/2013 |
| Country/Territory | International Bureau of the World Intellectual Property Organization (WIPO) |
| Priority date | 29/02/2012 |
| Priority number | EP20120157540 |
| Publication status | Published - 2013 |