Abstract
| Original language | English |
|---|---|
| IPC | B01L3/00 |
| Patent number | WO2012055415 |
| Filing date | 03/05/2012 |
| Country | Denmark |
| Publication status | Published - 2012 |
Bibliographical note
DTU reference nummer: 92542-10Cite this
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Microfluidic device and method for processing of macromolecules. / Kristensen, Anders (Inventor); Marie, Rodolphe (Inventor); Rasmussen, Kristian Hagsted (Inventor); Kalim Ullah, Mir (Inventor).
IPC No.: B01L3/00. Patent No.: WO2012055415. May 03, 2012.Research output: Patent
TY - PAT
T1 - Microfluidic device and method for processing of macromolecules
AU - Kristensen, Anders
AU - Marie, Rodolphe
AU - Rasmussen, Kristian Hagsted
AU - Kalim Ullah, Mir
N1 - DTU reference nummer: 92542-10
PY - 2012
Y1 - 2012
N2 - A microfluidic device and method for enzymatic processing of ultra-long macromolecules is disclosed. The device comprises a reaction chamber with a first manifold, a second manifold, and a plurality of reaction channels, each reaction channel extending from the first manifold to the second manifold. The device further comprises first inlet and outlet channels for filling the reaction channels via the manifolds with one or more macromolecule containers suspended in a first carrier fluid, wherein the first inlet and outlet channels are configured such that a flow established from the first set of inlets to the first set of outlets is guided through the reaction channels, and second inlet and outlet channels for feeding an enzymatic reagent to the reaction chamber essentially without displacing the macromolecule containers trapped in the reaction channels, wherein the second set of inlets and outlets are configured such that a flow established from the second inlet to the second outlet is guided through at least one of the manifolds and bypasses the reaction channels.
AB - A microfluidic device and method for enzymatic processing of ultra-long macromolecules is disclosed. The device comprises a reaction chamber with a first manifold, a second manifold, and a plurality of reaction channels, each reaction channel extending from the first manifold to the second manifold. The device further comprises first inlet and outlet channels for filling the reaction channels via the manifolds with one or more macromolecule containers suspended in a first carrier fluid, wherein the first inlet and outlet channels are configured such that a flow established from the first set of inlets to the first set of outlets is guided through the reaction channels, and second inlet and outlet channels for feeding an enzymatic reagent to the reaction chamber essentially without displacing the macromolecule containers trapped in the reaction channels, wherein the second set of inlets and outlets are configured such that a flow established from the second inlet to the second outlet is guided through at least one of the manifolds and bypasses the reaction channels.
M3 - Patent
M1 - WO2012055415
Y2 - 2012/05/03
ER -