Microbial production of the flavonoids garbanzol, resokaempferol and fisetin

Steen Gustav Stahlhut; Solvej Siedler; Ana Rute Neves; JEROME MAURY,; Jochen Förster; Paula Gaspar; Irina Borodina; Edith Angelica Rodriguez Prado; Tomas Strucko

Microbial production of the flavonoids garbanzol, resokaempferol and fisetin

Steen Gustav Stahlhut (Inventor)
, Solvej Siedler (Inventor)
, Ana Rute Neves (Inventor)
, JEROME MAURY, (Inventor)
, Jochen Förster (Inventor)
, Paula Gaspar (Inventor)
, Irina Borodina (Inventor)
, Edith Angelica Rodriguez Prado (Inventor)
, Tomas Strucko (Inventor)

Research output: Patent

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Abstract

The invention provides a genetically modified micro-organism comprising one or more transgene for the production of one or more of the flavonoids garbanzol, resokaempferol and fisetin. The micro-organism may be a bacterial or yeast cell engineered to express a metabolic pathway for garbanzol, resokaempferol and/or fisetin biosynthesis. The invention further provides a method for producing garbanzol, resokaempferol and/or fisetin employing the genetically modified micro-organism of the invention. The genetically modified micro- organism may be used to convert a number of substrates and/or co-substrates into fisetin via a fisetin biosynthetic pathway.

Original language	English
IPC	C07D 311/ 30 A I
Patent number	WO2016071505
Filing date	12/05/2016
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	11/06/2015
Priority number	EP20150171638
Publication status	Published - 12 May 2016

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title = "Microbial production of the flavonoids garbanzol, resokaempferol and fisetin",

abstract = "The invention provides a genetically modified micro-organism comprising one or more transgene for the production of one or more of the flavonoids garbanzol, resokaempferol and fisetin. The micro-organism may be a bacterial or yeast cell engineered to express a metabolic pathway for garbanzol, resokaempferol and/or fisetin biosynthesis. The invention further provides a method for producing garbanzol, resokaempferol and/or fisetin employing the genetically modified micro-organism of the invention. The genetically modified micro- organism may be used to convert a number of substrates and/or co-substrates into fisetin via a fisetin biosynthetic pathway.",

author = "Stahlhut, \{Steen Gustav\} and Solvej Siedler and Neves, \{Ana Rute\} and JEROME MAURY, and Jochen F{\"o}rster and Paula Gaspar and Irina Borodina and \{Rodriguez Prado\}, \{Edith Angelica\} and Tomas Strucko",

year = "2016",

month = may,

day = "12",

language = "English",

type = "Patent",

note = "WO2016071505; C07D 311/ 30 A I",

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TY - PAT

T1 - Microbial production of the flavonoids garbanzol, resokaempferol and fisetin

AU - Stahlhut, Steen Gustav

AU - Siedler, Solvej

AU - Neves, Ana Rute

AU - MAURY,, JEROME

AU - Förster, Jochen

AU - Gaspar, Paula

AU - Borodina, Irina

AU - Rodriguez Prado, Edith Angelica

AU - Strucko, Tomas

PY - 2016/5/12

Y1 - 2016/5/12

N2 - The invention provides a genetically modified micro-organism comprising one or more transgene for the production of one or more of the flavonoids garbanzol, resokaempferol and fisetin. The micro-organism may be a bacterial or yeast cell engineered to express a metabolic pathway for garbanzol, resokaempferol and/or fisetin biosynthesis. The invention further provides a method for producing garbanzol, resokaempferol and/or fisetin employing the genetically modified micro-organism of the invention. The genetically modified micro- organism may be used to convert a number of substrates and/or co-substrates into fisetin via a fisetin biosynthetic pathway.

AB - The invention provides a genetically modified micro-organism comprising one or more transgene for the production of one or more of the flavonoids garbanzol, resokaempferol and fisetin. The micro-organism may be a bacterial or yeast cell engineered to express a metabolic pathway for garbanzol, resokaempferol and/or fisetin biosynthesis. The invention further provides a method for producing garbanzol, resokaempferol and/or fisetin employing the genetically modified micro-organism of the invention. The genetically modified micro- organism may be used to convert a number of substrates and/or co-substrates into fisetin via a fisetin biosynthetic pathway.

M3 - Patent

M1 - WO2016071505

Y2 - 2016/05/12

ER -

Microbial production of the flavonoids garbanzol, resokaempferol and fisetin

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