Microbial production of the flavonoids garbanzol, resokaempferol and fisetin

Steen Gustav Stahlhut (Inventor), Solvej Siedler (Inventor), Ana Rute Neves (Inventor), JEROME MAURY, (Inventor), Jochen Förster (Inventor), Paula Gaspar (Inventor), Irina Borodina (Inventor), Edith Angelica Rodriguez Prado (Inventor), Tomas Strucko (Inventor)

Research output: Patent

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Abstract

The invention provides a genetically modified micro-organism comprising one or more transgene for the production of one or more of the flavonoids garbanzol, resokaempferol and fisetin. The micro-organism may be a bacterial or yeast cell engineered to express a metabolic pathway for garbanzol, resokaempferol and/or fisetin biosynthesis. The invention further provides a method for producing garbanzol, resokaempferol and/or fisetin employing the genetically modified micro-organism of the invention. The genetically modified micro- organism may be used to convert a number of substrates and/or co-substrates into fisetin via a fisetin biosynthetic pathway.

Original languageEnglish
IPCC07D 311/ 30 A I
Patent numberWO2016071505
Filing date12/05/2016
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date11/06/2015
Priority numberEP20150171638
Publication statusPublished - 12 May 2016

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