Micro-‘‘factory’’ for self-assembled peptide nanostructures

Jaime Castillo, Romén Rodriguez-Trujíllo, Sébastian Gauthier, Alexander C.Ø. Jensen, Winnie Edith Svendsen

    Research output: Contribution to journalConference articleResearchpeer-review

    Abstract

    This study describes an integrated micro ‘‘factory’’ for the preparation of biological self-assembled peptide nanotubes and nanoparticles on a polymer chip, yielding controlled growth conditions. Self-assembled peptides constitute attractive building blocks for the fabrication of biological nanostructures due to the mild conditions of their synthesis process. This biological material can form nanostructures in a rapid way and the synthesis method is less expensive as compared to that of carbon nanotubes or silicon nanowires. The present article thus reports on the on-chip fabrication of self-assembled peptide nanostructures by means of a microfluidic device that is able to resist the harsh conditions imposed by the solvent used during the nanostructure synthesis. This on-chip fabrication was found to be simple, rapid, and convenient.
    Original languageEnglish
    JournalMicroelectronic Engineering
    Volume88
    Issue number8
    Pages (from-to)1685-1688
    ISSN0167-9317
    DOIs
    Publication statusPublished - 2011
    Event36th International Conference on Micro- and Nano-Engineering - Genoa, Italy
    Duration: 19 Sep 201022 Sep 2010
    Conference number: 36
    http://www.mne2010.org/

    Conference

    Conference36th International Conference on Micro- and Nano-Engineering
    Number36
    CountryItaly
    CityGenoa
    Period19/09/201022/09/2010
    Internet address

    Keywords

    • On-chip fabrication
    • Microfluidics
    • Self-assembled peptides
    • Peptide nanoparticle
    • Peptide tube
    • Nanostructures

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