Three new natural products, 3,8-dimethoxy-5,7-dihydroxy-3',4'-methylenedioxyflavone, 3,6,8-trimethoxy-5,7-dihydroxy-3',4'-methylenedioxyflavone and 3,6,8,3',4'-pentamethoxy-5,7-dihydroxyflavone were isolated from Melicope coodeana syn. Euodia simplex (Rutaceae) along with 3,6,3-trimethoxy-5,7,4'-trihydroxyflavone and 3,3'-dimethoxy-5,7,4'-trihydroxyflavone. The structural assignments are based on 1H and 13C NMR data, including discussion of the chemical shifts of C-2 in 3,5-dihydroxy- and 3-methoxy-5-hydroxyflavones. The presence of highly methoxylated and methylenedioxyflavones is characteristic of the genus Melicope, and the present findings support the recent transfer of Euodia simplex to Melicope.
- Euodia simplex
- Melicope coodeana
- C-13 NMR
- Reunion Island
Simonsen, H. T., Larsen, M. D., Nielsen, M. W., Adsersen, A., Olsen, C. E., Strasberg, D., Smitt, U. W., & Jaroszewsk, J. W. (2002). Methylenedioxy- and methoxyflavones from Melicope coodeana syn. Euodia simplex. Phytochemistry, 60(8), 817-820. https://doi.org/10.1016/S0031-9422(02)00083-3