Methods for producing monoterpene indole alkaloids

Michael Krogh Jensen (Inventor), Lea Gram Hansen (Inventor), Jie Zhang (Inventor), Jay D Keasling (Inventor), Samuel Alan Bradley (Inventor), Vasil D'Ambrosio (Inventor), Nils Emil Junge Marcussen (Inventor)

Research output: Patent

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Abstract

The present invention relates to microorganisms for producing monoterpene indole al-kaloids (MIAs) and derivatives thereof de novo, including halogenated MIAs and halo-genated derivatives thereof. Also provided herein are methods for producing MIAs and derivatives thereof de novo, in particular halogenated MIAs and derivatives thereof, in a 5 microorganism, as well as useful nucleic acids, vectors and host cells for performing the present methods.

Original languageEnglish
Patent numberWO2023222879
Filing date07/07/2022
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date07/07/2022
Priority numberEP20220183656
Publication statusPublished - 23 Nov 2023

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