Methods for modeling chinese hamster ovary (cho) cell metabolism.

Markus Herrgard (Inventor), Lasse Ebdrup Pedersen (Inventor), Nathan E. Lewis (Inventor), Anders Bech Bruntse (Inventor)

Research output: Patent

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Embodiments of the present invention generally relate to the computational analysis and characterization biological networks at the cellular level in Chinese Hamster Ovary (CHO) cells. Based on computational methods utilizing a hamster reference genome, the invention provides methods for identifying a CHO cell line having a desired genetic trait, as well as for generating a desired CHO cell line having a genetic basis for a desired phenotype. Additionally, described herein are methods for constructing and analyzing in silico models of biological networks for CHO cells.
Original languageEnglish
Patent numberWO2015010088
Filing date22/01/2015
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date19/07/2013
Priority numberUS201361856526P
Publication statusPublished - 2015

Bibliographical note

Also published as: US2016160270 (A1) EP3022293 (A1)


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