Methods for modeling chinese hamster ovary (cho) cell metabolism.

Markus Herrgard (Inventor), Lasse Ebdrup Pedersen (Inventor), Nathan E. Lewis (Inventor), Anders Bech Bruntse (Inventor)

Research output: Patent

322 Downloads (Pure)

Abstract

Embodiments of the present invention generally relate to the computational analysis and characterization biological networks at the cellular level in Chinese Hamster Ovary (CHO) cells. Based on computational methods utilizing a hamster reference genome, the invention provides methods for identifying a CHO cell line having a desired genetic trait, as well as for generating a desired CHO cell line having a genetic basis for a desired phenotype. Additionally, described herein are methods for constructing and analyzing in silico models of biological networks for CHO cells.
Original languageEnglish
IPCC12N5/07
Patent numberWO2015010088
Filing date22/01/2015
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date19/07/2013
Priority numberUS201361856526P
Publication statusPublished - 2015

Bibliographical note

Also published as: US2016160270 (A1) EP3022293 (A1)

Cite this

Herrgard, M., Pedersen, L. E., Lewis, N. E., & Bruntse, A. B. (2015). IPC No. C12N5/07. Methods for modeling chinese hamster ovary (cho) cell metabolism. (Patent No. WO2015010088).