Methods for decoupling cell growth from production of biochemicals and recombinant polypeptides

Songyuan Li (Inventor), Christian Bille Jendresen (Inventor), Lasse Ebdrup Pedersen (Inventor), Jenny Marie Landberg (Inventor), Kristoffer Bach Falkenberg (Inventor), Hemanshu Mundhada (Inventor), Alex Toftgaard Nielsen (Inventor)

Research output: Patent

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Abstract

The present invention generally relates to industrial microbiology, and specifically to the production of biochemical compounds, such as L-serine, L-tyrosine, mevalonate and their derivatives, and recombinant polypeptides using genetically modified microorganisms. More particularly, the present invention pertains to the decoupling of cell growth from production of biochemical compounds, such as L-serine, L-tyrosine, mevalonate and their derivatives, in a microorganism by down regulating the nucleotide biosynthesis in said microorganism.
Original languageEnglish
IPCC12N1/21; C12N15/63; C12N9/88; C12P13/22; C12P21/02; C12P7/42
Patent numberWO2018020012
Filing date01/02/2018
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date29/07/2016
Priority numberEP20160182046
Publication statusPublished - 2018

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