Method for phenotyping using nmr spectroscopy

Bill Clark (Inventor), Klaes Golman (Inventor), Mathilde Hauge Lerche (Inventor), Mike Looker (Inventor), Mike O'Sullivan (Inventor), Albie Santos (Inventor), Rolf Servin (Inventor), Mikkel Thanning (Inventor), Jan Henrik Ardenkjær-Larsen (Inventor)

Research output: Patent

31 Downloads (Pure)


The invention relates to methods for phenotyping by determining protein activity in vivo using at least one probe compound and enhancing the nuclear polarisation of NMR active nuclei present in the probe compound (hereinafter termed "hyperpolarisation") prior to NMR analysis.

Original languageEnglish
IPCG01R 33/ 465 A I
Patent numberUS2005232864
Filing date13/05/2005
CountryUnited States
Priority date15/04/2003
Priority numberWO2003NO00126
Publication statusPublished - 20 Oct 2005
Externally publishedYes

Bibliographical note

Also published as: WO03089657 (A1) JP2005523442 (A) JP4424656 (B2) EP1501940 (A1) AU2003228150 (A1) AU2003228150 (A8)

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