Method for characterizing metabolic stability of a drug

Mathilde Hauge Lerche (Inventor), Klaes Golman (Inventor)

Research output: Patent

26 Downloads (Pure)

Abstract

An NMR based method for characterising the metabolic stability of a drug candidate comprising the steps of enhancing the nuclear polarisation of NMR active nuclei present in the drug candidate (hereinafter termed "hyperpolarisation"), contacting the drug candidate with liver cells or cell organelles, and carrying out NMR analysis.

Original languageEnglish
IPCG01R 33/ 62 A N
Patent numberUS2005170331
Filing date04/08/2005
Country/TerritoryUnited States
Priority date17/12/2003
Priority numberNO20030005626
Publication statusPublished - 4 Aug 2005
Externally publishedYes

Bibliographical note

Also published as: EP1544634 (A1), JP2005181332 (A)

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