Method and device for forming a concentration gradient for chemotactic evaluation through use of laminar flow

Ulrich Krühne (Inventor), Beyer Michael (Inventor), Thomas Ahl (Inventor)

Research output: Patent

30 Downloads (Pure)

Abstract

The invention relates to methods and devices for forming a concentration gradient of a reagent for use in chemotactic evaluation. A flow passage is provided and defined at least in part by a substrate having a target region on a surface thereof. A concentration gradient of a reagent is formed over the target region by controlled delivery of a fluid containing the reagent in laminar flow through the flow passage and over the target region. The concentration gradient is suitable for chemotactic evaluation. Typically, the inventive methods and devices are employed to evaluate the chemotactic interaction between a candidate compound and a monolayer of immobilized cells.
Original languageEnglish
IPCB01L3/00
Patent numberUS2003044879
Filing date06/03/2003
CountryUnited States
Publication statusPublished - 2003
Externally publishedYes

Bibliographical note

Patent application number: US20010941950 20010828

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