Method and apparatus for producing contrast agents for magnetic resonance imaging

Jan Henrik Ardenkjær-Larsen; Oskar Axelsson; Haukur Jóhannesson

Method and apparatus for producing contrast agents for magnetic resonance imaging

Jan Henrik Ardenkjær-Larsen (Inventor), Oskar Axelsson (Inventor), Haukur Jóhannesson (Inventor)

Research output: Patent

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Abstract

The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and a catalyst for the hydrogenation of a substrate compound, hydrogenating (110) the substrate with hydrogen gas (H2) enriched in para-hydrogen (p-1H2) to form a hydrogenated contrast agent and exposing (120, 305) the contrast agent to a sequence of pulses of magnetic field. The apparatus comprises a magnetic treatment unit (240) equipped with means for producing pulses of magnetic field.

Original language	English
IPC	A61B5/055; A61K49/00; A61K49/18; G01R33/28; (IPC1-7): A61K49/06
Patent number	WO2004019997
Filing date	11/03/2004
Priority date	29/08/2002
Priority number	GB20020019952
Publication status	Published - 2004

Bibliographical note

Also published as: AT355085 (T) AU2003264127 (A1) CN1694731 (A) DE60312172 (T2) EP1531872 (A1) EP1531872 (B1) JP2005536306 (A) US2006104906 (A1)

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title = "Method and apparatus for producing contrast agents for magnetic resonance imaging",

abstract = "The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and a catalyst for the hydrogenation of a substrate compound, hydrogenating (110) the substrate with hydrogen gas (H2) enriched in para-hydrogen (p-1H2) to form a hydrogenated contrast agent and exposing (120, 305) the contrast agent to a sequence of pulses of magnetic field. The apparatus comprises a magnetic treatment unit (240) equipped with means for producing pulses of magnetic field.",

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T1 - Method and apparatus for producing contrast agents for magnetic resonance imaging

AU - Ardenkjær-Larsen, Jan Henrik

AU - Axelsson, Oskar

AU - Jóhannesson, Haukur

N1 - Also published as: AT355085 (T) AU2003264127 (A1) CN1694731 (A) DE60312172 (T2) EP1531872 (A1) EP1531872 (B1) JP2005536306 (A) US2006104906 (A1)

PY - 2004

Y1 - 2004

N2 - The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and a catalyst for the hydrogenation of a substrate compound, hydrogenating (110) the substrate with hydrogen gas (H2) enriched in para-hydrogen (p-1H2) to form a hydrogenated contrast agent and exposing (120, 305) the contrast agent to a sequence of pulses of magnetic field. The apparatus comprises a magnetic treatment unit (240) equipped with means for producing pulses of magnetic field.

AB - The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and a catalyst for the hydrogenation of a substrate compound, hydrogenating (110) the substrate with hydrogen gas (H2) enriched in para-hydrogen (p-1H2) to form a hydrogenated contrast agent and exposing (120, 305) the contrast agent to a sequence of pulses of magnetic field. The apparatus comprises a magnetic treatment unit (240) equipped with means for producing pulses of magnetic field.

M3 - Patent

M1 - WO2004019997

Y2 - 2004/03/11

ER -

Method and apparatus for producing contrast agents for magnetic resonance imaging

Abstract

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