Method and apparatus for producing contrast agents for magnetic resonance imaging

Maurice Goldman (Inventor), Oskar Axelsson (Inventor), Haukur Jóhannesson (Inventor), Jan Henrik Ardenkjær-Larsen (Inventor)

Research output: Patent

21 Downloads (Pure)


The present invention relates to an arrangement and a method for providing contrast agent for e.g. MRI (Magnetic Resonance Imaging) and NMR (Nuclear Magnetic Resonance) applications. The method according to the invention comprises the steps of obtaining (100) a solution in a solvent of a hydrogenatable, unsaturated substrate compound and a catalyst for the hydrogenation of a substrate compound, hydrogenating (110) the substrate with hydrogen gas (H2) enriched in para-hydrogen (p-1H2) to form a hydrogenated contrast agent and exposing (120) the contrast agent to a oscillating magnetic field in combination with a stationary magnetic field. The apparatus comprises a magnetic treatment unit (240) equipped with means for producing an oscillating and a stationary magnetic field.
Original languageEnglish
IPCA61K49/00; A61K49/06; (IPC1-7): A61K49/00
Patent numberWO2004019995
Filing date11/03/2004
Priority date29/08/2002
Priority numberGB20020019954
Publication statusPublished - 2004

Bibliographical note

Also published as: WO2004019995 (A3) AT335514 (T) AU2003258687 (A1) AU2003258687 (A8) CN100335139 (C) CN1694730 (A) DE60307477 (T2) EP1531871 (A2) EP1531871 (B1) JP2006510585 (A) US2006127313 (A1)

Fingerprint Dive into the research topics of 'Method and apparatus for producing contrast agents for magnetic resonance imaging'. Together they form a unique fingerprint.

Cite this