Medium to large scale radioisotope production for targeted radiotherapy using a small PET cyclotron

Helge Thisgaard, Mikael Jensen, Dennis Ringkjøbing Elema

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    In recent years the use of radionuclides in targeted cancer therapy has increased. In this study we have developed a high-current solid target system and demonstrated that by the use of a typical low-energy medical cyclotron, it is possible to produce tens of GBq's of many unconventional radionuclides relevant for cancer therapy such as 64Cu and 119Sb locally at the hospitals.
    Original languageEnglish
    JournalApplied Radiation and Isotopes
    Volume69
    Issue number1
    Pages (from-to)1-7
    ISSN0969-8043
    DOIs
    Publication statusPublished - 2011

    Keywords

    • Sb-119
    • High powertarget
    • Radionuclide therapy
    • Cu-64
    • Auger electrons
    • DOTATATE

    Cite this

    @article{9232429430774b05956ba9c0af9ee1c0,
    title = "Medium to large scale radioisotope production for targeted radiotherapy using a small PET cyclotron",
    abstract = "In recent years the use of radionuclides in targeted cancer therapy has increased. In this study we have developed a high-current solid target system and demonstrated that by the use of a typical low-energy medical cyclotron, it is possible to produce tens of GBq's of many unconventional radionuclides relevant for cancer therapy such as 64Cu and 119Sb locally at the hospitals.",
    keywords = "Sb-119, High powertarget, Radionuclide therapy, Cu-64, Auger electrons, DOTATATE",
    author = "Helge Thisgaard and Mikael Jensen and Elema, {Dennis Ringkj{\o}bing}",
    year = "2011",
    doi = "10.1016/j.apradiso.2010.07.019",
    language = "English",
    volume = "69",
    pages = "1--7",
    journal = "Applied Radiation and Isotopes",
    issn = "0969-8043",
    publisher = "Pergamon Press",
    number = "1",

    }

    Medium to large scale radioisotope production for targeted radiotherapy using a small PET cyclotron. / Thisgaard, Helge; Jensen, Mikael; Elema, Dennis Ringkjøbing.

    In: Applied Radiation and Isotopes, Vol. 69, No. 1, 2011, p. 1-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

    TY - JOUR

    T1 - Medium to large scale radioisotope production for targeted radiotherapy using a small PET cyclotron

    AU - Thisgaard, Helge

    AU - Jensen, Mikael

    AU - Elema, Dennis Ringkjøbing

    PY - 2011

    Y1 - 2011

    N2 - In recent years the use of radionuclides in targeted cancer therapy has increased. In this study we have developed a high-current solid target system and demonstrated that by the use of a typical low-energy medical cyclotron, it is possible to produce tens of GBq's of many unconventional radionuclides relevant for cancer therapy such as 64Cu and 119Sb locally at the hospitals.

    AB - In recent years the use of radionuclides in targeted cancer therapy has increased. In this study we have developed a high-current solid target system and demonstrated that by the use of a typical low-energy medical cyclotron, it is possible to produce tens of GBq's of many unconventional radionuclides relevant for cancer therapy such as 64Cu and 119Sb locally at the hospitals.

    KW - Sb-119

    KW - High powertarget

    KW - Radionuclide therapy

    KW - Cu-64

    KW - Auger electrons

    KW - DOTATATE

    U2 - 10.1016/j.apradiso.2010.07.019

    DO - 10.1016/j.apradiso.2010.07.019

    M3 - Journal article

    VL - 69

    SP - 1

    EP - 7

    JO - Applied Radiation and Isotopes

    JF - Applied Radiation and Isotopes

    SN - 0969-8043

    IS - 1

    ER -