Mechanistic investigation of the gold-catalyzed aerobic oxidation of aldehydes: added insight from Hammett studies and isotopic labelling experiments

Peter Fristrup; Louise Bahn Johansen; Claus Hviid Christensen

doi:10.1039/b803270j

Mechanistic investigation of the gold-catalyzed aerobic oxidation of aldehydes: added insight from Hammett studies and isotopic labelling experiments

Peter Fristrup
, Louise Bahn Johansen
, Claus Hviid Christensen

Department of Chemistry

Technical University of Denmark

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

The gold-catalyzed aerobic oxidation of aldehydes proceeds through development of a partial negative charge and has a significant kinetic isotope effect (k(H)/k(D) = 2.8-2.9), which illustrates that activation of the C-H bond takes place in the rate-determining step.

Original language	English
Journal	Chemical Communications
Issue number	24
Pages (from-to)	2750-2752
ISSN	1359-7345
DOIs	https://doi.org/10.1039/b803270j
Publication status	Published - 2008

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title = "Mechanistic investigation of the gold-catalyzed aerobic oxidation of aldehydes: added insight from Hammett studies and isotopic labelling experiments",

abstract = "The gold-catalyzed aerobic oxidation of aldehydes proceeds through development of a partial negative charge and has a significant kinetic isotope effect (k(H)/k(D) = 2.8-2.9), which illustrates that activation of the C-H bond takes place in the rate-determining step.",

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AU - Christensen, Claus Hviid

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AB - The gold-catalyzed aerobic oxidation of aldehydes proceeds through development of a partial negative charge and has a significant kinetic isotope effect (k(H)/k(D) = 2.8-2.9), which illustrates that activation of the C-H bond takes place in the rate-determining step.

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DO - 10.1039/b803270j

M3 - Journal article

C2 - 18688298

SN - 1359-7345

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EP - 2752

JO - Chemical Communications

JF - Chemical Communications

IS - 24

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Mechanistic investigation of the gold-catalyzed aerobic oxidation of aldehydes: added insight from Hammett studies and isotopic labelling experiments

Abstract

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