Measurements of dermal uptake of nicotine directly from air and clothing

Gabriel Bekö, Glenn C. Morrison, Charles J. Weschler, Holger Martin Koch, Tunga Salthammer, Tobias Schripp, Jørn Toftum, Geo Clausen

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    Dermal uptake directly from air is a significant contributor to total exposure for certain organic compounds, and has been recently experimentally verified for two phthalates. The objective of the current study was to investigate whether airborne nicotine can be dermally absorbed. Two bare-skinned subjects together with a subject wearing clean clothes were dermally exposed to environmental tobacco smoke (ETS) for three hours in a climate chamber; during the exposure all three subjects breathed clean air through hoods covering their heads. The clothed subject later repeated his exposure wearing a shirt previously exposed to tobacco smoke. Urine samples were subsequently analyzed for nicotine and two of its metabolites. The results demonstrate that nicotine can be dermally absorbed directly from air at rates comparable to passive smoking. Wearing clean clothes significantly decreases uptake, while wearing exposed clothes results in substantial uptake.
    Original languageEnglish
    Title of host publicationProceedings of Indoor Air 2016
    Number of pages2
    Publication date2016
    Article number241
    Publication statusPublished - 2016
    Event14th international conference on Indoor Air Quality and Climate - Ghent, Belgium
    Duration: 3 Jul 20168 Jul 2016
    Conference number: 14

    Conference

    Conference14th international conference on Indoor Air Quality and Climate
    Number14
    Country/TerritoryBelgium
    CityGhent
    Period03/07/201608/07/2016

    Keywords

    • Exposure Pathway
    • Biomonitoring
    • Indoor Environment
    • E-cigarettes

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