Markers of basement membrane remodelling are associated with higher mortality in patients with advanced carotid atherosclerosis

I. Goncalves, S. Holm Nielsen, C. Tengryd, S. Brix, A. Edsfeldt, F. Genovese, E. Bengtsson, M. Karsdal, D. Julie Leeming, J. Nilsson

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Abstract

Background: Patients with atherosclerosis have a known increased risk of cardiovascular events and early mortality. The atherosclerotic disease is characterized by accumulation of lipids, cells and proteins in the arterial wall, which includes remodelling of the extracellular matrix (ECM). Laminin and collagen type IV are the main ECM structural proteins present in the arterial basement membrane.
Original languageEnglish
Article number4982
JournalEuropean Heart Journal
Volume39
Issue numbersuppl_1
Pages (from-to)1039-1040
ISSN0195-668X
DOIs
Publication statusPublished - 2018
EventESC Congress 2018 - Munich, Germany
Duration: 25 Aug 201829 Aug 2018

Conference

ConferenceESC Congress 2018
Country/TerritoryGermany
CityMunich
Period25/08/201829/08/2018

Keywords

  • Carotid atherosclerosis
  • Mortality
  • Basement membrane

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