Manipulation of ionic liquid anion-solute-antisolvent interactions for the purification of acetaminophen

C. C. Weber; Andreas Jonas Kunov-Kruse; R. D. Rogers; A. S. Myerson

doi:10.1039/c5cc00198f

Manipulation of ionic liquid anion-solute-antisolvent interactions for the purification of acetaminophen

C. C. Weber
, Andreas Jonas Kunov-Kruse
, R. D. Rogers
, A. S. Myerson

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Hydrogen bond donating cosolvents have been shown to significantly reduce the solubility of acetaminophen (AAP) in ionic liquids containing the acetate anion. Reduced solubility arises from competition for solvation by the acetate anion and can be used for the design of advanced separation techniques, illustrated by the crystallization of AAP.

Original language	English
Journal	Chemical Communications
Volume	51
Issue number	20
Pages (from-to)	4294-4297
Number of pages	4
ISSN	1359-7345
DOIs	https://doi.org/10.1039/c5cc00198f
Publication status	Published - 2015
Externally published	Yes

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title = "Manipulation of ionic liquid anion-solute-antisolvent interactions for the purification of acetaminophen",

abstract = "Hydrogen bond donating cosolvents have been shown to significantly reduce the solubility of acetaminophen (AAP) in ionic liquids containing the acetate anion. Reduced solubility arises from competition for solvation by the acetate anion and can be used for the design of advanced separation techniques, illustrated by the crystallization of AAP.",

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AU - Weber, C. C.

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AU - Rogers, R. D.

AU - Myerson, A. S.

PY - 2015

Y1 - 2015

N2 - Hydrogen bond donating cosolvents have been shown to significantly reduce the solubility of acetaminophen (AAP) in ionic liquids containing the acetate anion. Reduced solubility arises from competition for solvation by the acetate anion and can be used for the design of advanced separation techniques, illustrated by the crystallization of AAP.

AB - Hydrogen bond donating cosolvents have been shown to significantly reduce the solubility of acetaminophen (AAP) in ionic liquids containing the acetate anion. Reduced solubility arises from competition for solvation by the acetate anion and can be used for the design of advanced separation techniques, illustrated by the crystallization of AAP.

U2 - 10.1039/c5cc00198f

DO - 10.1039/c5cc00198f

M3 - Journal article

C2 - 25673089

SN - 1359-7345

VL - 51

SP - 4294

EP - 4297

JO - Chemical Communications

JF - Chemical Communications

IS - 20

ER -

Manipulation of ionic liquid anion-solute-antisolvent interactions for the purification of acetaminophen

Abstract

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