Abstract
We identified a malignant lymphoma infiltrating the lung, liver, kidney, mesenteric lymph nodes, and eye as the cause of death in a male West Indian manatee (Trichechus manatus). Diagnosis was based on gross histopathologic, and immunohistochemical studies. Tissue samples from ten organs were included in a tissue microarray and sections from this array were subjected to immunohistochemical staining. The cytoplasm of the neoplastic lymphocytes identified in six organs was positive for CD3, a marker for T-cell differentiation. The neoplastic cells were negative for CD79 alpha, a marker for B-cell differentiation. The cause of this neoplasm was not determined. This is the first report of malignant lymphoma in the mammal order Sirenia.
Original language | English |
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Journal | Journal of Wildlife Diseases |
Volume | 41 |
Issue number | 4 |
Pages (from-to) | 834-838 |
ISSN | 0090-3558 |
Publication status | Published - 2005 |
Keywords
- tissue microarray
- Trichechus manatus
- lymphoma
- case history
- West Indian manatee