Malignant lymphoma in a west Indian manatee (Trichechus manatus)

Anne Sofie Hammer, Bjarne Klausen, Steffen Knold, Hans H. Dietz, Stephen J. Hamilton Dutoit

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    We identified a malignant lymphoma infiltrating the lung, liver, kidney, mesenteric lymph nodes, and eye as the cause of death in a male West Indian manatee (Trichechus manatus). Diagnosis was based on gross histopathologic, and immunohistochemical studies. Tissue samples from ten organs were included in a tissue microarray and sections from this array were subjected to immunohistochemical staining. The cytoplasm of the neoplastic lymphocytes identified in six organs was positive for CD3, a marker for T-cell differentiation. The neoplastic cells were negative for CD79 alpha, a marker for B-cell differentiation. The cause of this neoplasm was not determined. This is the first report of malignant lymphoma in the mammal order Sirenia.
    Original languageEnglish
    JournalJournal of Wildlife Diseases
    Volume41
    Issue number4
    Pages (from-to)834-838
    ISSN0090-3558
    Publication statusPublished - 2005

    Keywords

    • tissue microarray
    • Trichechus manatus
    • lymphoma
    • case history
    • West Indian manatee

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