Abstract
Perinatal disturbances of brain hemodynamics can have a detrimental effect on the brain's parenchyma with consequently adverse neurodevelopmental outcome. Noninvasive, reliable tools to evaluate the neonate's brain hemodynamics are scarce. Advances in magnetic resonance imaging have provided new methods to noninvasively assess brain hemodynamics. More recently these methods have made their transition to the neonatal population. The aim of this review is twofold. Firstly, to describe these newly available noninvasive methods to investigate brain hemodynamics in neonates. Secondly, to discuss the results that were obtained with these techniques, identifying both potential clinical applications as well as gaps of knowledge.
| Original language | English |
|---|---|
| Journal | Pediatric Research |
| Volume | 80 |
| Issue number | 5 |
| Pages (from-to) | 641-650 |
| ISSN | 0031-3998 |
| DOIs | |
| Publication status | Published - 2016 |
| Externally published | Yes |
Keywords
- Pediatrics, Perinatology and Child Health
- Radiation biology - Radiation and isotope techniques
- Nervous system - Physiology and biochemistry
- Nervous system - Pathology
- Pediatrics
- Animals, Chordates, Humans, Mammals, Primates, Vertebrates
- adverse neurodevelopmental outcome
- neural hemodynamics
- PEDIATRICS
- CEREBRAL-BLOOD-FLOW
- HYPOXIC-ISCHEMIC ENCEPHALOPATHY
- NEAR-INFRARED SPECTROSCOPY
- CONGENITAL HEART-DISEASE
- LABELING PERFUSION MRI
- OXYGEN-CONSUMPTION
- QUANTITATIVE ASSESSMENT
- NEWBORN-INFANTS
- PRETERM INFANTS
- ARTERIAL-BLOOD