Abstract
Objective: We sought to assess whether magnetic resonance imaging (MRI) at 3.0 T detects more brain lesions in acute optic neuritis (ON) than MRI at 1.5 T.
Materials and Methods: Twenty-eight patients with acute ON were scanned at both field-strengths using fast-fluid-attenuated inversion recovery (FLAIR), proton density and T2-weighted turbo spin echo, and T1-weighted spin echo after contrast. In addition, magnetization-prepared rapid acquisition gradient echo (MPRAGE) was obtained after contrast at 3.0 T. Lesion number and volumes were
assessed by an observer blind to patient identity and field strength.
Results: Scans at 3.0 T showed a significantly increase in number of lesions detected on FLAIR images (P 0.002) relative to scanning at 1.5 T. MPRAGE proved to be suitable for detecting enhancing lesions in ON.
Conclusion: The MRI protocol at 3.0 T was more sensitive to hyperintense brain lesions in ON than the standard MRI protocol at 1.5 T.
Keyword: Multiple sclerosis,High field,Optic neuritis,Magnetic resonance imaging,
Keyword: Multiple sclerosis,High field,Optic neuritis,Magnetic resonance imaging,
Original language | English |
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Journal | Investigative Radiology |
Volume | 41 |
Issue number | 2 |
Pages (from-to) | 76-82 |
ISSN | 0020-9996 |
Publication status | Published - 2006 |
Externally published | Yes |