Magnetic bead micromixer: Influence of magnetic element geometry and field amplitude

Torsten Lund-Olesen, Bjarke B. Buus, Jakob Howalt, Mikkel Fougt Hansen

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    Abstract

    A scheme for the silicon microfabrication of lab-on-a-chip systems with mixing based on dynamic plugs of magnetic beads is presented. The systems consist of a microfluidic channel integrated with a number of soft magnetic elements by the sides of the channel. The elements are magnetized by a homogeneous external ac magnetic field. The systems are scalable with respect to the number of magnetic bead plugs and number of parallel channels, and thus they have high potential for use in biological separation using functionalized magnetic beads. The mixing efficiency is characterized for two different geometries of the soft magnetic structures and found to be highly sensitive to the geometry and position of the structures.
    Original languageEnglish
    JournalJournal of Applied Physics
    Volume103
    Issue number7
    Pages (from-to)07E902
    ISSN0021-8979
    DOIs
    Publication statusPublished - 2008

    Bibliographical note

    Copyright (2008) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.

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