Magic Numbers in Protein Structures

Per-Anker Lindgård, Henrik Bohr

    Research output: Contribution to journalJournal articleResearchpeer-review

    246 Downloads (Pure)

    Abstract

    A homology measure for protein fold classes has been constructed by locally projecting consecutive secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of domains containing magic numbers of secondary structures and multipla of these domains. We have performed a statistical analysis of available protein structures and found agreement with the predicted preferred abundances. Furthermore, a connection between sequence information and fold classes is established in terms of hinge forces between the structural elements.
    Original languageEnglish
    JournalPhysical Review Letters
    Volume77
    Issue number4
    Pages (from-to)779-782
    ISSN0031-9007
    DOIs
    Publication statusPublished - 1996

    Bibliographical note

    Copyright (1996) American Physical Society.

    Keywords

    • SECONDARY STRUCTURE
    • GLOBULAR-PROTEINS
    • STABILITY

    Fingerprint Dive into the research topics of 'Magic Numbers in Protein Structures'. Together they form a unique fingerprint.

    Cite this